Uveitis
Background:
\- Uveitis is a general term describing a group of inflammatory diseases of the eye. The causes of uveitis …
Bethesda, United StatesCompleted Jun 29, 2022
Inflammatory Bowel Diseases (IBD)Crohn DiseaseColitis, Ulcerative
Difficult-to-treat inflammatory bowel disease (DTT-IBD) represents a heterogeneous group of patients with treatment-refr…
Multiple LocationsEst. completion Oct 31, 2032
Inflammatory Bowel Disease
This study evaluates oral Lactobacillus reuteri as an adjunct therapy for 2 months. Endoscopic assessments will be perfo…
Suqian, ChinaCompleted Mar 30, 2026
HypertensionDiabetes
Background:
* Type 2 diabetes (T2D) and associated complications are major contributors to the global disease burden. T…
Accra, Ghana
Infantile Colic
Academic, independent, non-commercial, multicenter study sponsored by the Department of Translational Medical Sciences (…
Naples, ItalyEst. completion Jul 2027
Healthy VolunteerObestity
Background:
Many people in the United States are overweight or obese. This natural history study will look into how lif…
Phoenix, United StatesEst. completion Jan 30, 2027
AsthmaChronic Obstructive Pulmonary Disease (COPD)Lung Cancer
Wildfire smoke (WFS) is the leading climate-related risk in Canada and the main source of harmful air pollution. While s…
Vancouver, CanadaEst. completion Aug 31, 2029
Healthy Volunteer
Background:
As people age, the cells in the pancreas that produce insulin begin to release less of this hormone, and le…
Baltimore, United StatesEst. completion Mar 31, 2027
Recurrent C. Difficile (rCDI)Ulcerative Colitis (UC)Metabolic Syndrome (MetS)
The gut microbiota plays a key role in immunity and metabolism and contributes to diseases such as recurrent C. difficil…
Rome, ItalyEst. completion Jan 19, 2029
FrailtySarcopenia
Fibroblast Growth Factor 19 (FGF-19) is an intestinal hormone secreted in the post-prandial state, whose primary role is…
Pierre-Bénite, FranceEst. completion Mar 16, 2028
End-stage Renal Disease (ESRD)Kidney Transplantation
Chronic kidney disease affects approximately 10% of the world population. End-stage renal disease (ESRD) is associated w…
Lyon, FranceEst. completion Oct 15, 2028
Non-GI CancersCancer of Gastrointestinal TractGastrointestinal Cancer
Background:
\- Gastrointestinal cancers can occur in the throat, stomach, gallbladder, liver, pancreas, and colon. Rese…
Bethesda, United States
Lumbar Degenerative DiseaseLumbar SpondylolisthesisLumbar Disc Herniation
Patients undergoing open posterior lumbar fusion surgery often experience postoperative gastrointestinal problems, such …
Kunming, ChinaCompleted Dec 31, 2025
Rheumatoid Arthritis
Personalized medicine in which each patient would receive the ideal personalized treatment and regimen, holds great prom…
Montpellier, FranceCompleted Sep 16, 2026
Obesity
The aim of this trial is to investigate whether regular endurance exercise during the lactation period will influence br…
Trondheim, NorwayEst. completion Nov 24, 2025
Clostridium Difficile Infection
This is a Phase 1, first-in-human, double-blind, placebo-controlled, adaptive-design, single-site study, involving dose …
Knoxville, United StatesEst. completion Aug 22, 2028
ImmunosuppressionPeriodontal DiseaseHealthy SubjectsHealthy Volunteer
Background:
\- Gum disease is a condition in which the tissue around the tooth root becomes swollen and infected. This …
Bethesda, United States
Recurrent Ascending Cholangitis After Biliary-enteric Anastomosis
This single-center prospective randomized controlled trial plans to recruit 60 adult patients with recurrent ascending c…
Multiple LocationsEst. completion Oct 2027
Recurrent Bacterial Vaginosis
This randomized clinical trial aims to compare the recurrence of bacterial vaginosis (BV) in women receiving probiotics …
Multan, PakistanCompleted Jan 31, 2026
EczemaDermatitisSkin Diseases, GeneticDermatitis, AtopicSkin Diseases
Background:
\- Atopic dermatitis, or eczema, is a chronic skin disorder. Patients sometimes have infections with S. aur…
Bethesda, United StatesEst. completion Jan 1, 2027