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Data source: ClinicalTrials.gov
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Showing 11472 microbiome trials
Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar IntakePhase 1Recruiting
Diet TherapyHealthy Volunteers
Background: Diet is one of the most modifiable behaviors affecting health. But diet assessment measures that are based …
Phoenix, United StatesEst. completion Jan 1, 2028
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AIM-MET: AI-Guided Microbiome-Targeted Nutrition for Glycemic Improvement in Type 2 DiabetesRecruiting
Type 2 DiabetesDiabetes Mellitus Type 2
AIM-MET is a randomized clinical study testing whether a fixed microbiome-targeted nutritional product can improve blood…
Izmir, Turkey (Türkiye)Est. completion Mar 30, 2027
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A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier HomeostasisRecruiting
Inflammatory Bowel Disease
Crohn's Disease (CD) and Ulcerative Colitis (UC), collectively known as inflammatory bowel disease (IBD), are two of the…
Chicago, United StatesEst. completion Sep 1, 2026
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Effects of Gallotannins on the Gut Microbiome and How it Affects Inflammatory Markers Among Obese Individuals.Recruiting
Obesity (Disorder)
The goal of this clinical trial is to understand how gallotannin-rich (GT-rich) mangoes can reduce the inflammatory mark…
Prairie View, United StatesEst. completion Jun 2026
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Abnormal Food Timing and Circadian Dyssynchrony in Alcohol Induced Colon CarcinogenesisRecruiting
Colorectal Cancer
The purpose of this study is to study the impact of Western lifestyle, including moderate alcohol consumption and delaye…
Chicago, United StatesEst. completion May 31, 2023
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Patient Derived Preclinical ModelsRecruiting
Cancer
Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with…
Rochester, United StatesEst. completion Mar 31, 2027
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Almonds, Gut Microbiome and KidsRecruiting
DysbiosisCardiometabolic Health Indicators
This 8-week parallel-arm randomized controlled trial (N=70; ages 6-13) will determine the impact of daily almond butter …
Tallahassee, United StatesEst. completion Aug 31, 2028
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Characterization of the IFN-I Response in Subjects Who Experienced Severe or Mild Forms of COVID-19Recruiting
COVID-19
Type I interferon (IFN-I) production is triggered by the detection of viral molecules, such as strands of viral RNA or D…
Lyon, FranceEst. completion Jun 2027
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Validation of the Association Between the Abundance of Three Bacterial Genera in Stool Samples and the Risk of Gallbladder Cancer in South American Patients With GallstonesCompleted
Gallbladder Malignant Neoplasm
In our previous work, we found three types of bacteria in stool samples from South American patients with gallstones lin…
Cochabamba, BoliviaCompleted Jan 31, 2026
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Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical TrialRecruiting
Healthy Volunteer
Background: As people age, the cells in the pancreas that produce insulin begin to release less of this hormone, and le…
Baltimore, United StatesEst. completion Mar 31, 2027
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The Effect of Synbiotic and Diet Modification Among Overweight or Obese Hong Kong ChineseRecruiting
Obesity
Synbiotic is a nutritional supplement that contains both prebiotic and probiotic. Probiotics are beneficial microorganis…
Shatin, Hong KongEst. completion Dec 31, 2028
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Fecal Microbiota Transplantation in Children With ASDRecruiting
Autism Spectrum Disorder
This is a single-center, randomized, double-dummy, triple-blind, placebo-controlled, three-arm parallel-group superiorit…
Shenzhen, ChinaEst. completion Dec 31, 2026
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Adding a Live Biotherapeutic Product (CBM588) to Pembrolizumab for the Treatment of Renal Cell Cancer After SurgeryPhase 2Recruiting
Clear Cell Renal Cell CarcinomaSarcomatoid Renal Cell CarcinomaStage II Renal Cell Cancer AJCC v8Stage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8
This phase II trial compares the effect of adding a Live Biotherapeutic Product called CBM588 to pembrolizumab versus pe…
Duarte, United StatesEst. completion Oct 24, 2028
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Effects of Treatments on Atopic DermatitisPhase 2Recruiting
EczemaDermatitisSkin Diseases, GeneticDermatitis, AtopicSkin Diseases
Background: \- Atopic dermatitis, or eczema, is a chronic skin disorder. Patients sometimes have infections with S. aur…
Bethesda, United StatesEst. completion Jan 1, 2027
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Akkermansia Muciniphila (AKK) for Radiation-Induced Skin InjuryPhase 1Recruiting
Radiation-Induced Skin Injury
This study is a multicenter, open-label, Phase I single-arm clinical trial evaluating the safety and tolerability of a t…
Chengdu, ChinaEst. completion Nov 30, 2026
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Probiotic Intervention in ConstipationRecruiting
Gastrointestinal Function
To evaluate the effects of probiotic intervention on gastrointestinal function in patients with constipation after 4 wee…
Multiple LocationsEst. completion Dec 1, 2026
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Protective Ileostomy Versus Protective Colostomy in Anterior Rectal ResectionRecruiting
Stoma ColostomyStoma Ileostomy
Loop ileostomy and loop colostomy are both used as protective stomas after anterior resection. There is a lack of eviden…
Helsinki, FinlandEst. completion Oct 2028
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Adults With ConstipationRecruiting
Constipation
This randomized, double-blind, placebo-controlled trial will assess the clinical effects of Akk09 in adults with functio…
Suzhou, ChinaEst. completion Mar 1, 2027
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Efficacy of Probiotics for OAB Patients With AnxietyRecruiting
Overactive Bladder (OAB)
The goal of this clinical trial is to learn if probiotics can help improve symptoms in adults with overactive bladder (O…
Jinan, ChinaEst. completion Dec 31, 2028
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Faecal Microbiota Transplantation After Allogeneic Stem Cell TransplantationPhase 2Recruiting
Acute Leukemia in RemissionMyelodysplastic SyndromesMyeloproliferative SyndromeHodgkin LymphomaLymphoma, Non-HodgkinMyelomaChronic Lymphocytic Leukemia
The aim of this study is to assess the Fecal Microbiota Transplantation (FMT) efficacy in the prevention of allogeneic h…
Amiens, FranceEst. completion May 2030
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