Condition Guides

Learn how your gut microbiome is connected to your condition, what researchers have discovered, and find clinical trials that might be right for you.

Inflammatory Bowel Disease (IBD)
Restoring balance to a disrupted gut

IBD is a group of chronic inflammatory conditions of the digestive tract. Emerging research shows the gut microbiome plays a central role — and new trials are exploring microbiome therapies that could change treatment forever.

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Irritable Bowel Syndrome (IBS)
Calming the gut-brain storm

IBS affects millions worldwide with symptoms that can be debilitating, yet the underlying cause has long been mysterious. New research points to the gut microbiome and the gut-brain axis as key drivers — and trials are finding promising paths to relief.

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Crohn's Disease
Tackling one of the gut's toughest conditions

Crohn's disease causes inflammation anywhere along the digestive tract and can be a serious, lifelong condition. Microbiome research is illuminating why some people develop Crohn's — and opening doors to new therapies.

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Ulcerative Colitis
From chronic flares to lasting remission

Ulcerative colitis (UC) causes inflammation and ulcers in the colon lining, leading to painful flares. Of all IBD conditions, UC has seen some of the most exciting microbiome trial results — with FMT achieving remission in multiple studies.

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C. difficile (C. diff)
The condition where microbiome therapy works best

C. difficile is a dangerous bacterial infection that thrives when the gut microbiome is disrupted — often after antibiotic use. FMT has become a landmark treatment, with cure rates over 90% in clinical trials.

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Small Intestinal Bacterial Overgrowth (SIBO)
When good bacteria end up in the wrong place

SIBO occurs when bacteria that normally live in the colon migrate into the small intestine, causing fermentation, malabsorption, and pain. The microbiome connection here is front and center — and new trials are exploring targeted treatments.

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Obesity & Metabolic Health
Your gut microbiome and your metabolism are deeply linked

Obesity is far more than a calorie equation. The trillions of microbes in the gut influence how energy is extracted from food, how fat is stored, and even how hungry you feel. Microbiome-targeted therapies may transform metabolic health.

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Mental Health & Gut-Brain Axis
The surprising conversation between your gut and your brain

Up to 95% of serotonin is made in the gut. The gut-brain axis is a two-way communication highway that influences mood, anxiety, and cognitive function. Microbiome research in mental health is one of the most exciting frontiers in medicine.

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Cancer & the Microbiome
The microbiome as ally in the fight against cancer

The gut microbiome influences cancer risk, treatment response, and side effect profiles. From colorectal cancer to immunotherapy outcomes, microbiome science is reshaping oncology — and clinical trials are uncovering how to harness it.

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Autism Spectrum & the Gut
Exploring the gut-brain link in autism

Up to 70% of people with autism experience GI symptoms, and researchers are uncovering profound differences in gut microbiome composition. Microbiome therapies targeting autism are among the most closely watched trials in the field.

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