C. difficile is a dangerous bacterial infection that thrives when the gut microbiome is disrupted — often after antibiotic use. FMT has become a landmark treatment, with cure rates over 90% in clinical trials.
C. diff infection is almost entirely caused by microbiome disruption. Antibiotics wipe out protective gut bacteria, leaving a vacuum that C. difficile colonizes and exploits. Restoring a healthy, diverse microbiome — through FMT or next-generation microbiome therapies like SER-109 — directly displaces C. diff and prevents relapse.