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Data source: ClinicalTrials.gov
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Showing 18750 trials for Cancer
Feasibility Study of a Transition Pathway at Discharge From Full Hospitalization in OncologyRecruiting
Cancer
Patient reported outcomes (PRO) measure the health status directly reported by the patients, without external interpreta…
Nîmes, FranceEst. completion Dec 2028
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Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLCPhase 2Recruiting
Metastatic Non-Squamous Non-Small Cell Lung CancerAdult Solid Tumor
This is an exploratory, signal-finding, randomized, placebo-controlled, blinded, multi-center phase 2b trial of the anti…
Birmingham, United StatesEst. completion Oct 1, 2029
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Combining High-frequency Micro-ultrasound and Multiparametric MRI Target Biopsy for Detecting Prostate CancerRecruiting
Prostatic Neoplasm of Uncertain Behavior
\*\*Study Goal:\*\* The purpose of this clinical trial is to determine if combining high-frequency micro-ultrasound with…
Salzburg, AustriaEst. completion Nov 1, 2027
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Synovial Sarcoma Registry / Biospecimen RepositoryRecruiting
Synovial Sarcoma
The purpose of this study is to collect and store data and samples for future research to attempt to improve outcomes fo…
Philadelphia, United StatesEst. completion Jun 2028
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Comparison of Double-tract and Tubular Gastric Anastomosis in Proximal Gastric CancerRecruiting
Gastric Cancer (GC)Double-tract ReconstructionTubular Gastric Anastomosis
This study includes patients diagnosed with proximal gastric cancer (Siewert type II/III, cT1-3N0-1M0) across six tertia…
Jinan, ChinaEst. completion May 1, 2027
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Immune Metabolism Dysregulation and Efficacy to Anti-PD-1 PD-L1 Agents in Non Small Cell Lung Cancer PatientsRecruiting
Nsclc
Prospective, biological, observational study involving the collection and use of samples from patients suffering from NS…
Rome, ItalyEst. completion Jul 24, 2026
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Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast CancerPhase 3Recruiting
Breast Cancer
The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regiona…
Fairbanks, United StatesEst. completion Sep 1, 2027
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Hepatic Arterial Infusion Chemotherapy Plus Envafolimab and Lenvatinib for First-Line Unresectable Advanced Biliary Tract CancerPhase 1Recruiting
Biliary Tract Cancer
Advanced biliary tract cancer has a poor prognosis and limited efficacy with current regimens. This multicenter single-a…
Chengdu, ChinaEst. completion Mar 2029
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Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1Recruiting
MesotheliomaFamilies
Background: -A gene provides instructions to the body. Mutated genes can sometimes cause cancer. Germline mutations are…
Bethesda, United StatesEst. completion Jul 6, 2026
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A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung CancerPhase 2Recruiting
Small Cell Lung Cancer
Small cell lung cancer (SCLC) is characterized by aggressive and rapid growth and a tendency to develop early spread to …
New Haven, United StatesEst. completion May 2029
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Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.Phase 1Recruiting
GEP-NETGastroenteropancreatic Neuroendocrine TumorGastroenteropancreatic Neuroendocrine Tumor DiseaseNeuroendocrine TumorsCarcinoidCarcinoid TumorPancreatic NETSolid TumorSomatostatin Receptor
The primary objectives are to determine the recommended Phase 2 dose (RP2D) and optimal treatment regimen, characterize …
Iowa City, United StatesEst. completion Feb 2027
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LYL273 for Patients With Relapsed or Refractory mCRCPhase 1Recruiting
Colorectal Cancer
This is a Phase 1/2 open-label, multicenter study evaluating the safety and efficacy of LYL273 in participants with rela…
Duarte, United StatesEst. completion Jun 2028
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Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic MalignanciesPhase 1Recruiting
Malignancy, HematologicNeoplasms, HematologicNeoplasms, HematopoieticBlood CancerHematological NeoplasmsHematopoietic MalignanciesDysmyelopoietic SyndromesHematopoetic MyelodysplasiaMyeloid Leukemia, AcuteNonlymphoblastic Leukemia, AcuteLeukemia, Lymphocytic, Acute
Background: Blood cancers (such as leukemias) can be hard to treat, especially if they have mutations in the TP53 or RA…
Bethesda, United StatesEst. completion Apr 30, 2029
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CAR 70-BCMA CAR-T Cells for the Treatment of Relapsed or Refractory Plasma Cell NeoplasmsEARLY_PHASE1Recruiting
Relapsed or Refractory Plasma Cell Neoplasms
This is a single arm study to evaluate the safety and efficacy of CAR70-BCMA dual-target CAR-T cell therapy for relapsed…
Chengdu, ChinaEst. completion Apr 1, 2027
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Ex Vivo Expansion (ACT-X)Recruiting
Solid TumorHealthyMalignant Solid Neoplasm
The purpose of this study is to understand how the body's immune cells respond to a new type of vaccine (neoantigen vacc…
Jacksonville, United StatesEst. completion Oct 31, 2028
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Screening for Lung Cancer in Subjects With Family History of Lung CancerRecruiting
Lung Cancer
Lung cancer can be detected via screening of high-risk individuals, i.e current or ex-heavy smokers, with low-dose compu…
Hong Kong, Hong KongEst. completion Apr 2028
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A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade GliomaPhase 1Recruiting
Glioblastoma Multiforme of BrainGliomaGlioblastoma
This is an open-label, multicenter dose-escalation study to be followed by a dose expansion to define the optimal dose o…
Tampa, United StatesEst. completion Jun 2027
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A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)Phase 2Recruiting
Non-small Cell Lung Cancer
This trial will evaluate the efficacy and safety of various therapies in participants with Stage IB, IIA, IIB, IIIA, or …
Duarte, United StatesEst. completion Nov 30, 2026
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A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate CancerPhase 1Recruiting
Prostate Cancer
This study is being conducted to learn more about the safety, tolerability, and effectiveness of an experimental treatme…
Orlando, United StatesEst. completion Mar 29, 2029
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A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent GlioblastomaPhase 2Recruiting
Glioblastoma
Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/…
Birmingham, United StatesEst. completion Jun 2028
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