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Data source: ClinicalTrials.gov
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Showing 2104 trials for Crohn's Disease
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)Phase 3Recruiting
Crohn's Disease
The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to s…
Dothan, United StatesEst. completion Oct 30, 2028
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Risankizumab for Refractory Perianal Fistulizing Crohn's DiseasePhase 4Recruiting
Crohn DiseasePerianal FistulaPerianal Fistula Due to Crohn's DiseasePerianal Crohn's Disease
Crohn's disease is an inflammatory bowel disease characterized by relapses and remissions, causing lesions throughout th…
Nishinomiya, JapanEst. completion Oct 13, 2028
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A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's DiseasePhase 4Recruiting
Crohn's Disease
The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with ada…
Dothan, United StatesEst. completion Jun 28, 2027
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MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT)Recruiting
Antiphospholipid (aPL)-PositiveRheumatic ArthritisCeliac DiseaseFocal Segmental Glomerulosclerosis (FSGS)Membranous NephropathyCrohn Disease (CD)Type 1 Diabetes MellitusAlport SyndromePompe DiseaseAlzheimer s DiseaseUrea Cycle DisorderSystem Lupus ErythematosusHyperlipidemiaInherited ThrombophiliaSickle Cell Disease (SCD)Parkinson Disease (PD)
The primary objective of this multicenter observational registry is to characterize the clinical, epidemiological, and b…
Amman, JordanEst. completion Oct 2028
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Longitudinal Immunophenotyping of Patients With Inflammatory Bowel DiseaseRecruiting
Inflammatory Bowel DiseaseCrohn's DiseaseUlcerative Colitis
Background: Inflammatory bowel disease (IBD) is a term used to describe disorders that cause long-term inflammation in …
Bethesda, United StatesEst. completion Jun 1, 2036
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Addressing Disability Effectively With Psychosocial TelemedicineCompleted
Crohn Disease
This multi-site study will be implemented at 5 gastroenterology practices to recruit 420 adults with IBD to complete a b…
Philadelphia, United StatesCompleted Jan 31, 2024
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Visceral Sensitivity in IBD (Irritable Bowel Disease) and IBS (Irritable Bowel Syndrome)Recruiting
IBSUlcerative Colitis, ActiveUlcerative Colitis, Remission (3a: With IBS Symptoms, 3b: Without IBS Symptoms)Healthy ControlsCrohn's Disease, ActiveCrohn's Disease, Remission (6a: With IBS Symptoms, 6b: Without IBS Symptoms)
Aim: More insight in pathogenesis of IBS and IBD. Samples are collected in context of an European research project.
Leuven, BelgiumEst. completion Jan 2099
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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's DiseasePhase 2Recruiting
Colitis, UlcerativeCrohn Disease
Study IIBD is a master protocol that will support a collection of individual sub studies that share key design component…
Scottsdale, United StatesEst. completion Jun 2027
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A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative ColitisRecruiting
Crohn DiseaseColitis, Ulcerative
The purpose of this study is to estimate and compare the incidence of overall malignancy, serious infection, and opportu…
Houston, United StatesEst. completion Aug 31, 2029
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A Study to Investigate the Long-term Safety, Tolerability and Efficacy of Balinatunfib in Participants With Crohn's Disease or Ulcerative Colitis (SPECIFI-IBD-LTS)Phase 2TERMINATED
Colitis UlcerativeCrohn's Disease
LTS19689 is a multinational, multicenter extension study to evaluate the long-term safety, tolerability and efficacy of …
Southlake, United StatesCompleted Sep 29, 2026
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Validation and Clinical Impact of GLIM Criteria in Patients With Inflammatory Bowel DiseaseRecruiting
Inflammatory Bowel DiseasesCrohn DiseaseColitis, Ulcerative (UC)Malnutrition
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are chronic inflammatory conditions…
Multiple LocationsEst. completion Nov 2027
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Effect of the Consumption of a Probiotic Strain on the Prevention of Post-operative Recurrence in Crohn's DiseaseCompleted
Crohn's Disease
A double-blind, multicentre, stratified by centre, randomised, parallel study with two groups of adult patients operated…
Lille, FranceCompleted Mar 2007
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An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Crohn's Disease
This is a multinational, multicenter, randomized, double-blind, placebo-controlled, Phase 3 induction study, comprised o…
Peoria, United StatesEst. completion May 14, 2029
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A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Crohn's Disease
This is a multicenter, randomized, double-blind, placebo-controlled, maintenance, Phase 3 study to evaluate the efficacy…
Colorado Springs, United StatesEst. completion Aug 13, 2029
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Virtual hIStology of Crohn's Disease Ex-vivo Resected Anatomical LesionsRecruiting
Crohn Disease (CD)
Crohn's disease is a chronic, incurable inflammatory bowel disease with an unpredictable course, characterized by altern…
Vandœuvre-lès-Nancy, FranceEst. completion Oct 1, 2027
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The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 )Phase 3TERMINATED
Crohn Disease
The purpose of this study is to determine if vitamin D as an adjuvant therapy can improve the outcome (i.e. fewer relaps…
Edmonton, CanadaCompleted Sep 29, 2023
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Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative ColitisPhase 2Recruiting
Crohn's DiseaseUlcerative Colitis
Crohn's disease (CD) and Ulcerative colitis (UC) are 2 types of inflammatory bowel diseases which cause long-lasting, se…
Dothan, United StatesEst. completion Oct 2031
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Impact of Ultra-Processed Food Reduction on Remission Duration in Pediatric Crohn's DiseaseRecruiting
Crohn Disease (CD)
Crohn's disease is a chronic inflammatory bowel disease. This study will investigate whether reducing the intake of ultr…
Prague, CzechiaEst. completion Dec 31, 2027
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Microencapsulated Sodium Propionate in IBD Microbiota ModulationRecruiting
Crohn Disease
The goal of this clinical trial is to evaluate whether microencapsulated sodium propionate can modulate the gut microbio…
Padova, ItalyEst. completion Nov 30, 2028
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A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community SettingPhase 4Recruiting
Ulcerative ColitisCrohn's Disease
Ulcerative Colitis (UC) and Crohn's Disease (CD) are long-term conditions in the gut that can cause diarrhea, swelling (…
Birmingham, United StatesEst. completion May 1, 2027
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