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Showing 2058 trials for Crohn's Disease
Autologous Stem Cells in the Management of Fistulating Perianal Crohn's DiseaseWITHDRAWN
Fistula in AnoCrohn Disease
Crohn's disease is a chronic inflammatory condition that can affect any part of the bowel which can be controlled by a c…
Multiple LocationsCompleted Jun 11, 2026
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Longitudinal Immunophenotyping of Patients With Inflammatory Bowel DiseaseRecruiting
Inflammatory Bowel DiseaseCrohn's DiseaseUlcerative Colitis
Background: Inflammatory bowel disease (IBD) is a term used to describe disorders that cause long-term inflammation in …
Bethesda, United StatesEst. completion Jun 1, 2036
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A Study on Infections in Adults With Ulcerative Colitis/Crohn's DiseaseRecruiting
Ulcerative ColitisCrohn's Disease
More older people (more than 65 years of age) around the world are getting Ulcerative Colitis (UC) or Crohn's Disease (C…
Cambridge, United StatesEst. completion Dec 15, 2026
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A Specific Probiotic in thE MOdulation of Gut Microbiota of patieNts With Mild-to-modErate Ulcerative ColitisRecruiting
Ulcerative ColitisCrohn Disease
Probiotics are live microorganisms that provide health benefits when consumed in sufficient amounts. Traditional probiot…
Roma, ItalyEst. completion Sep 14, 2026
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A Study to Evaluate the Long-Term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's DiseasePhase 2Recruiting
Crohn DiseaseColitis, Ulcerative
The primary objective of the study is to evaluate the efficacy of 2 different maintenance dose regimens of TEV-48574 sub…
San Diego, United StatesEst. completion Jan 5, 2026
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Autologous Stem Cell Transplant for Crohn's DiseasePhase 2Recruiting
Crohn Disease
Crohn's Disease (CD) is an inflammatory bowel disease. It can lead to significant complications and discomfort in the st…
New York, United StatesEst. completion Oct 2028
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A Study of CDPATH™ to Help Manage and Treat Crohn's DiseasePhase 4Recruiting
Crohn's Disease
CDPATH™ is a tool to help predict the potential for developing Crohn's disease related complications in certain adult pa…
Phoenix, United StatesEst. completion Sep 12, 2026
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Developing a Self-Management Intervention to Improve Health Outcomes for Patients With Inflammatory Bowel DiseaseRecruiting
Inflammatory Bowel DiseasesUlcerative ColitisCrohn Disease
This research is studying whether changing an individual's behaviors may have an impact as a treatment or outcome for in…
Ann Arbor, United StatesEst. completion Mar 2028
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A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Moderately to Severely Active Crohns Disease
This Phase III, multicenter, double-blind, placebo-controlled treat-through study will evaluate the efficacy and safety …
Dothan, United StatesEst. completion Dec 31, 2028
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A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community SettingPhase 4Recruiting
Ulcerative ColitisCrohn's Disease
Ulcerative Colitis (UC) and Crohn's Disease (CD) are long-term conditions in the gut that can cause diarrhea, swelling (…
Birmingham, United StatesEst. completion Oct 1, 2027
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A Phase 2a Safety and Efficacy Open-Label Study of Tulisokibart (MK-7240/PRA023) in Participants With Moderately to Severely Active Crohn's Disease (MK-7240-006)Phase 2Completed
Crohn Disease
The purpose of this study is to assess the safety and efficacy of tulisokibart (MK-7240) in participants with moderately…
Los Angeles, United StatesCompleted Sep 23, 2022
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Characterization of Colorectal Dysplasic Lesions and Stratification of Their Evolving Risk in Inflammatory Bowel Disease Patients: a Prospective, Observational and Multicenter StudyRecruiting
Crohn Disease (CD)Colitis Ulcerative
Inflammatory Bowel Disease (IBD) patients have an increased risk of ColoRectal Cancer (CRC). The cumulative risk of CRC …
Multiple LocationsEst. completion Sep 15, 2033
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Cranberry and Gut Health in Crohn's DiseaseEARLY_PHASE1Recruiting
Crohn Disease (CD)Crohn Disease
This study is investigating whether a cranberry-based dietary supplement, rich in polyphenols and fiber, can enhance gut…
Worcester, United StatesEst. completion Aug 15, 2026
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A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's DiseasePhase 2Recruiting
Inflammatory Bowel DiseasesCrohn's Disease
This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety o…
Lancaster, United StatesEst. completion Sep 2028
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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's DiseasePhase 2Recruiting
Colitis, UlcerativeCrohn Disease
Study IIBD is a master protocol that will support a collection of individual sub studies that share key design component…
Scottsdale, United StatesEst. completion Jun 2027
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Evaluation of the Accuracy of Immunostaining of Claudin 2 to Detect Active or Inactive Inflammation in Endoscopic Biopsies of IBDRecruiting
Ulcerative Colitis (UC)Crohn Disease
In view of the increasing evidence of the importance of mucosal healing as a combination of endoscopic and histologic he…
San Donato Milanese, ItalyEst. completion Feb 2027
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Immune Regulation in Ulcerative Colitis or Crohn s DiseaseRecruiting
Inflammatory Bowel DiseaseUlcerative ColitisChrohn's Disease
This study will investigate in patients with Crohn s disease and ulcerative colitis how the body s immune system control…
Bethesda, United States
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A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's DiseasePhase 2Recruiting
Crohn Disease
The main purpose of this study is to see how the safety and efficacy of a farnesoid X receptor (FXR) agonist (LY4395089)…
Scottsdale, United StatesEst. completion Jun 2027
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IBS-Oriented CDED Versus Low FODMAP Diet for Irritable Bowel SyndromeRecruiting
Irritable Bowel Syndrome (IBS)
Background: Irritable Bowel Syndrome (IBS) affects approximately 4.1% of the global population and imposes a significant…
Multiple LocationsEst. completion Jul 30, 2028
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Assessment and Educational Intervention to Reduce Ultra-processed Food Consumption in Pediatric Patients With IBDRecruiting
IBDCrohn Disease (CD)Ulcerative Colitis (UC)Inflammatory Bowel Disease (IBD)Ultra Processed FoodNutrition AssessmentDGBI
This study explores whether simple nutrition education can help children and teens with inflammatory bowel disease (IBD)…
Hartford, United StatesEst. completion Dec 1, 2026
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