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Data source: ClinicalTrials.gov
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Showing 307 trials for Crohn's Disease
A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier HomeostasisRecruiting
Inflammatory Bowel Disease
Crohn's Disease (CD) and Ulcerative Colitis (UC), collectively known as inflammatory bowel disease (IBD), are two of the…
Chicago, United StatesEst. completion Sep 1, 2026
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TNFi Plus Low-Dose Upadacitinib vs TNFi Intensification in Crohn's Disease With Suboptimal ResponsePhase 4Recruiting
Crohn Disease (CD)
This multicenter, randomized, controlled trial aims to evaluate the efficacy and safety of standard-dose tumor necrosis …
Guangzhou, ChinaEst. completion Dec 31, 2028
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A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)Phase 3Recruiting
Crohn's Disease
The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to s…
Dothan, United StatesEst. completion Oct 30, 2028
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A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Crohn Disease
The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to…
Anaheim, United StatesEst. completion Jun 12, 2028
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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Moderately to Severely Active Crohns Disease
This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction t…
Glendale, United StatesEst. completion Dec 31, 2028
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A Phase I Study to Evaluate the Safety/Tolerability of BDHK-2009 Tablets in Healthy AdultPhase 1Recruiting
Ulcerative Colitis (UC)Ulcerative Colitis (Disorder)Ulcerative Colitis AcuteIBD (Inflammatory Bowel Disease)CD - Crohn's Disease
A Phase 1, 2-part, randomised, double-blind, placebo-controlled, FIH study to determine the safety, tolerability, and PK…
Hangzhou, ChinaEst. completion Dec 31, 2026
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A Study to Observe Real-world Evidence of Guselkumab Treatment in Participants With Ulcerative Colitis and Crohn's Disease in the United Kingdom (UK)Recruiting
Inflammatory Bowel DiseaseColitis, UlcerativeCrohn's Disease
The purpose of this study is to evaluate the clinical effectiveness (how well the treatment works) of Guselkumab, by lin…
Harrow, United KingdomEst. completion Mar 5, 2029
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A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Crohn Disease
The purpose of this study is to assess how well guselkumab works when compared to risankizumab in participants with mode…
Dothan, United StatesEst. completion Nov 15, 2028
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Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's DiseasePhase 2Recruiting
Crohn's Disease
Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tra…
Dothan, United StatesEst. completion Jan 2030
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A Study to Evaluate the Efficacy of Guselkumab in Chinese Participants With Crohn's Disease (CD)Phase 4Recruiting
Crohn Disease
The purpose of this study is to evaluate how well guselkumab works in participants with Crohn's disease (CD; a long-term…
Guangzhou, ChinaEst. completion Sep 15, 2027
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A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's DiseasePhase 2Recruiting
Crohn Disease
The purpose of this study is to evaluate how-well icotrokinra works (clinical efficacy) and how safe it is (safety) in p…
Chandler, United StatesEst. completion Sep 19, 2028
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Immune Regulation in Ulcerative Colitis or Crohn s DiseaseRecruiting
Inflammatory Bowel DiseaseUlcerative ColitisChrohn's Disease
This study will investigate in patients with Crohn s disease and ulcerative colitis how the body s immune system control…
Bethesda, United States
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Amitriptyline for IBS-like Symptoms in Quiescent Crohn's DiseasePhase 2Recruiting
Quiescent Crohn's Disease (CD)
Many individuals with Crohn's disease continue to experience abdominal pain, bloating, or bowel habit changes even when …
Ann Arbor, United StatesEst. completion Dec 2029
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Evaluation of Therapeutic Strategy to Prevent Crohn's Disease Endoscopic poSToperatIve recurreNce Based on earlY Dosage of Faecal CalprotectinRecruiting
Crohn Disease (CD)Ileocolic ResectionPost-endoscopic Operative Reccurence
Crohn's disease (CD) (\> 200,000 patients in France) is a chronic inflammatory disease that can lead to progression of i…
Amiens, FranceEst. completion Mar 1, 2027
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A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Crohn's Disease
The purpose of this study is to evaluate the clinical and endoscopic efficacy of guselkumab in pediatric participants wi…
Los Angeles, United StatesEst. completion Oct 27, 2027
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Tolerance of Local Administration of Cryopreserved Autologous Stromal Vascular Fraction Combined With Micrograft for the Treatment of Refractory Ano-perineal Fistulas in Crohn's DiseasePhase 1Recruiting
Crohn Disease (CD)
The ADICROHN-3 study is a prospective, multicenter, open-label cohort study. Its design is supported by the following e…
Marseille, FranceEst. completion Jun 29, 2028
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A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in GermanyRecruiting
Inflammatory Bowel DiseaseColitis, UlcerativeCrohn's Disease
The purpose of this study is to characterize participants with Crohn's Disease (CD) and Ulcerative Colitis (UC) treated …
Berlin, GermanyEst. completion Jan 15, 2029
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Moving Beyond Inflammation as a Therapeutic Target for Crohn's DiseasePhase 2Recruiting
Crohn Disease (CD)
The purpose of this research study is to evaluate what type of treatment will be beneficial for people with Crohn's dise…
Beverly Hills, United StatesEst. completion May 2028
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A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's DiseasePhase 2Recruiting
Crohn Disease
The main purpose of this study is to see how the safety and efficacy of a farnesoid X receptor (FXR) agonist (LY4395089)…
Scottsdale, United StatesEst. completion Jun 2027
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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's DiseasePhase 2Recruiting
Colitis, UlcerativeCrohn Disease
Study IIBD is a master protocol that will support a collection of individual sub studies that share key design component…
Scottsdale, United StatesEst. completion Jun 2027
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Recruitment Status