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Showing 321 trials for Crohn's Disease
A Clinical Trial of Taibowei® Adalimumab Injection in the Treatment of Chinese Pediatric Patients With Moderately to Severely Active Crohn's DiseasePhase 4Recruiting
Children Aged 6 Years and Above With Moderate - to - Severe Active Crohn's Disease
This study is a real - world clinical research of adalimumab. The project plans to enroll 30 subjects, aiming to evaluat…
Guangzhou, ChinaEst. completion Mar 2029
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IBD Strong Peer2Peer for Self-Management of Psychological DistressRecruiting
Inflammatory Bowel DiseasesUlcerative ColitisCrohn Disease
Psychological distress (PD) as a result of inflammatory bowel disease (IBD) is prevalent and associated with worse disea…
Halifax, CanadaEst. completion Mar 2027
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Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)Phase 3Recruiting
Crohn DiseaseColitis, Ulcerative
Researchers want to learn more about tulisokibart (also known as MK-7240) in an extension study. Tulisokibart is a medic…
Bristol, United StatesEst. completion Dec 17, 2037
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A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's DiseasePhase 4Recruiting
Crohn's Disease
The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with ada…
Dothan, United StatesEst. completion Jun 28, 2027
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Feasibility of a Minimally Invasive Diagnostic Algorithm in Suspected Crohn's DiseaseRecruiting
Crohn's Disease
The goal of this clinical trial is to learn whether a camera pill examination of the whole bowel can be used to diagnose…
Esbjerg, DenmarkEst. completion Aug 31, 2027
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A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)Phase 3Recruiting
Crohn's Disease
The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to s…
Dothan, United StatesEst. completion Oct 30, 2028
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Standardized Microbiota Transplant Therapy in Crohn's DiseasePhase 2Recruiting
Crohn Disease
Crohn's disease (CD) develops because of a disruption of homeostasis between the gut microbiota and the host immune syst…
Minneapolis, United StatesEst. completion Jun 15, 2029
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A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's DiseasePhase 2Recruiting
Crohn Disease
The main purpose of this study is to see how the safety and efficacy of a farnesoid X receptor (FXR) agonist (LY4395089)…
Scottsdale, United StatesEst. completion Jun 2027
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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's DiseasePhase 2Recruiting
Colitis, UlcerativeCrohn Disease
Study IIBD is a master protocol that will support a collection of individual sub studies that share key design component…
Scottsdale, United StatesEst. completion Jun 2027
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A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for Induction and Maintenance Therapy in Children With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Moderately to Severely Active Crohns Disease
This phase III, double-blind, multi-center treat-through study will evaluate the efficacy and safety of Afimkibart (also…
New York, United StatesEst. completion May 31, 2030
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Human Mass Balance Study of [14C] Ontunisertib in Healthy VolunteersPhase 1Recruiting
Fibrostenotic Crohn's Disease
This is an open, two-part study in healthy male volunteers, aged 30-65 years. This trial aims to understand how the hum…
Nottingham, United KingdomEst. completion Sep 26, 2026
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Clostridium Butyricum in Stenosing Crohn's DiseasePhase 1Recruiting
Crohn Disease (CD)
Crohn's disease is a condition of unknown etiology with an immune-mediated pathogenesis. The subgroup of Crohn's disease…
Roma, ItalyEst. completion Dec 31, 2026
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A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's DiseasePhase 2Recruiting
Inflammatory Bowel DiseasesCrohn's Disease
This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety o…
Lancaster, United StatesEst. completion Sep 2028
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Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or OverweightPhase 3Recruiting
Crohn's DiseaseObesity or Overweight
The main purpose of this study is to evaluate the efficacy and safety of mirikizumab and placebo compared with mirikizum…
Dothan, United StatesEst. completion May 2028
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Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative ColitisPhase 2Recruiting
Crohn's DiseaseUlcerative Colitis
Crohn's disease (CD) and Ulcerative colitis (UC) are 2 types of inflammatory bowel diseases which cause long-lasting, se…
Dothan, United StatesEst. completion Oct 2031
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Comparison Between Artificial Intelligence and Standard Reading to Investigate Suspected Crohn Disease: the SCAI STUDYRecruiting
Crohn Disease (CD)
The diagnosis of Crohn's Disease (CD) is based on a combination of clinical, biochemical (serological and fecal), endosc…
Brescia, ItalyEst. completion Dec 31, 2027
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Immune Regulation in Ulcerative Colitis or Crohn s DiseaseRecruiting
Inflammatory Bowel DiseaseUlcerative ColitisChrohn's Disease
This study will investigate in patients with Crohn s disease and ulcerative colitis how the body s immune system control…
Bethesda, United States
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DB-3Q for the Treatment of Medically Refractory Crohn's DiseasePhase 2Recruiting
Crohn Disease (CD)
This research study is studying DB-3Q as a possible treatment for medically refractory Crohn's disease. The purpose of t…
St Louis, United StatesEst. completion Jun 2027
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A Study Comparing Transperineal Ultrasound, Magnetic Resonance Imaging, Endoscopic Ultrasound, and Examination Under Anesthesia to Detect and Classify Perianal Fistulas in Patients With Crohn's Disease or Fistulas of Unknown CauseRecruiting
Crohn Disease (CD)Cryptoglandular Perianal Fistula
The goal of this study is to learn how well different imaging tests detect and describe perianal fistulas in adults with…
Hyderabad, IndiaEst. completion Apr 15, 2027
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Switching to the IL-23 Inhibitor Guselkumab for People With Active IBD Who Previously Used Ustekinumab (SHIFT-IBD)Recruiting
Inflammatory Bowel Disease (IBD)Crohn Disease (CD)Ulcerative Colitis (UC)IBD-unclassified (IBD-U)
The SHIFT-IBD Study is being conducted at multiple medical centers across Canada to evaluate how well guselkumab (Tremfy…
Calgary, CanadaEst. completion Nov 1, 2027
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Recruitment Status