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Data source: ClinicalTrials.gov
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Showing 4048 trials for IBD
Longitudinal Immunophenotyping of Patients With Inflammatory Bowel DiseaseRecruiting
Inflammatory Bowel DiseaseCrohn's DiseaseUlcerative Colitis
Background: Inflammatory bowel disease (IBD) is a term used to describe disorders that cause long-term inflammation in …
Bethesda, United StatesEst. completion Jun 1, 2036
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A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier HomeostasisRecruiting
Inflammatory Bowel Disease
Crohn's Disease (CD) and Ulcerative Colitis (UC), collectively known as inflammatory bowel disease (IBD), are two of the…
Chicago, United StatesEst. completion Sep 1, 2026
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Effects of Gallotannins on the Gut Microbiome and How it Affects Inflammatory Markers Among Obese Individuals.Recruiting
Obesity (Disorder)
The goal of this clinical trial is to understand how gallotannin-rich (GT-rich) mangoes can reduce the inflammatory mark…
Prairie View, United StatesEst. completion Jun 2026
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Urinary PGE-MUM as a Marker for Ulcerative Colitis ActivityRecruiting
Ulcerative Colitis (UC)
Ulcerative colitis (UC) is a chronic inflammatory bowel disease that requires regular monitoring of disease activity. Cu…
Asyut, EgyptEst. completion Jan 31, 2027
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Chronotherapy of 5-Aminosalicylic Acid in Ulcerative ColitisRecruiting
Ulcerative Colitis
The hypothesis of this study is that appropriate time of day of administration of oral, once daily 5-ASA therapy in alig…
Chicago, United StatesEst. completion Aug 30, 2026
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TNFi Plus Low-Dose Upadacitinib vs TNFi Intensification in Crohn's Disease With Suboptimal ResponsePhase 4Recruiting
Crohn Disease (CD)
This multicenter, randomized, controlled trial aims to evaluate the efficacy and safety of standard-dose tumor necrosis …
Guangzhou, ChinaEst. completion Dec 31, 2028
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AIM-IBD: A Microbiome-Targeted Supplement in Mild-to-Moderate Ulcerative ColitisRecruiting
Ulcerative Colitis (UC)Inflammatory Bowel Disease (IBD)Colitis
This Phase 2b randomized, double-blind, placebo-controlled, multicenter trial will evaluate the efficacy and safety of a…
Izmir, Turkey (Türkiye)Est. completion May 30, 2027
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VIBRANT-IBD: Brain Effects of Non-Invasive Vagus Nerve Stimulation in IBD RemissionEARLY_PHASE1ENROLLING_BY_INVITATION
Inflammatory Bowel Diseases (IBD)Remission of IBDIn AdultsInflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis)Crohn's Disease (CD)Ulcerative Colitis (UC)
The VIBRANT-IBD study is a pilot, prospective, single-arm feasibility study investigating the effects of non-invasive va…
Gdansk, PolandCompleted Dec 15, 2026
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Aquamin® for Prevention of Ulcerative Colitis J-Pouch-associate Intestinal InflammationPhase 2Recruiting
Ulcerative ColitisIleal Pouch
Ulcerative colitis (UC) is a disease that causes long-term inflammation in the digestive tract, and many people with thi…
Ann Arbor, United StatesEst. completion May 2029
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Proof of Concept Study Evaluating the Efficacy and Safety of ATH-063 Treatment in Patients With Relapsed/Refractory Moderately to Severely Active Ulcerative Colitis (UC)Phase 2Recruiting
Ulcerative ColitisInflammatory Bowel DiseasesAutoimmune Diseases
The primary objective of this trial is to evaluate the clinical efficacy of ATH-063 in participants with biologic/advanc…
Miami, United StatesEst. completion Dec 14, 2028
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A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative ColitisPhase 2Recruiting
Ulcerative ColitisInflammatory Bowel DiseasesColitisColitis, Ulcerative
This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active…
Canoga Park, United StatesEst. completion Jun 2026
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A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)Phase 3Recruiting
Crohn's Disease
The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to s…
Dothan, United StatesEst. completion Oct 30, 2028
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A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's DiseasePhase 2Recruiting
Crohn's Disease
The purpose of this study is to evaluate the efficacy of JNJ-78934804 at Week 48 compared to guselkumab and golimumab.
Birmingham, United StatesEst. completion May 23, 2025
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A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative ColitisPhase 3Recruiting
Colitis, Ulcerative
The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to…
Anaheim, United StatesEst. completion Aug 11, 2028
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A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative ColitisPhase 3Recruiting
Colitis, Ulcerative
The purpose of this study is to evaluate the efficacy, including clinical remission of guselkumab subcutaneous (SC) indu…
Litchfield Park, United StatesEst. completion Apr 2, 2024
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A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Crohn Disease
The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to…
Anaheim, United StatesEst. completion Jun 12, 2028
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A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative ColitisPhase 2Recruiting
Colitis, Ulcerative
The purpose of this study is to evaluate the efficacy and safety of JNJ-78934804 as compared to guselkumab and golimumab…
Arcadia, United StatesEst. completion May 15, 2025
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A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's DiseasePhase 2Recruiting
Crohn's Disease
The purpose of this study is to evaluate the clinical efficacy (GALAXI 1), clinical and endoscopic efficacy (GALAXI 2 an…
Dothan, United StatesEst. completion Oct 20, 2023
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GI Permeability Change in Response to Aquamin®Phase 2Completed
Ulcerative ColitisHealthyIrritable Bowel Syndrome With Diarrhea
This trial is being completed to learn about how Aquamin® affects gastrointestinal permeability, or the control of mater…
Ann Arbor, United StatesCompleted Mar 11, 2024
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A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative ColitisPhase 2Recruiting
Ulcerative Colitis
The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment…
Little Rock, United StatesEst. completion Jun 16, 2029
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