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Showing 4108 trials for IBD
Autologous Stem Cells in the Management of Fistulating Perianal Crohn's DiseaseWITHDRAWN
Fistula in AnoCrohn Disease
Crohn's disease is a chronic inflammatory condition that can affect any part of the bowel which can be controlled by a c…
Multiple LocationsCompleted Jun 11, 2026
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Combination CurQD and Vedolizumab in Ulcerative ColitisPhase 4Recruiting
Ulcerative Colitis
The purpose of this research study is to test the efficacy and safety of the study intervention, CurQD or placebo (non-a…
New York, United StatesEst. completion Jun 23, 2027
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Longitudinal Immunophenotyping of Patients With Inflammatory Bowel DiseaseRecruiting
Inflammatory Bowel DiseaseCrohn's DiseaseUlcerative Colitis
Background: Inflammatory bowel disease (IBD) is a term used to describe disorders that cause long-term inflammation in …
Bethesda, United StatesEst. completion Jun 1, 2036
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A Study on Infections in Adults With Ulcerative Colitis/Crohn's DiseaseRecruiting
Ulcerative ColitisCrohn's Disease
More older people (more than 65 years of age) around the world are getting Ulcerative Colitis (UC) or Crohn's Disease (C…
Cambridge, United StatesEst. completion Dec 15, 2026
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A Specific Probiotic in thE MOdulation of Gut Microbiota of patieNts With Mild-to-modErate Ulcerative ColitisRecruiting
Ulcerative ColitisCrohn Disease
Probiotics are live microorganisms that provide health benefits when consumed in sufficient amounts. Traditional probiot…
Roma, ItalyEst. completion Sep 14, 2026
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A Study to Evaluate the Long-Term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's DiseasePhase 2Recruiting
Crohn DiseaseColitis, Ulcerative
The primary objective of the study is to evaluate the efficacy of 2 different maintenance dose regimens of TEV-48574 sub…
San Diego, United StatesEst. completion Jan 5, 2026
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Autologous Stem Cell Transplant for Crohn's DiseasePhase 2Recruiting
Crohn Disease
Crohn's Disease (CD) is an inflammatory bowel disease. It can lead to significant complications and discomfort in the st…
New York, United StatesEst. completion Oct 2028
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Study of XmAb942 in Healthy Participants and Participants With Ulcerative ColitisPhase 1Recruiting
Ulcerative Colitis (UC)
The Phase 1 study described herein will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of XmAb…
Scottsdale, United StatesEst. completion Apr 2028
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Efficacy and Safety of Guselkumab in Patients With Moderate-to-Severe Ulcerative Colitis:A Real-World Prospective Cohort Study.Recruiting
Ulcerative Colitis (Disorder)Guselkumab
In a real-world setting, this study systematically evaluates the clinical efficacy and safety of guselkumab (GUS) in the…
Wenzhou, ChinaEst. completion Dec 31, 2028
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Development and External Validation of a Machine Learning Model for Pre-Endoscopic Prediction of Montreal Disease Extent (E1/E2/E3) in Ulcerative Colitis Using Symptoms, Signs, and Laboratory Tests: A Multicenter Retrospective Observational StudyRecruiting
Ulcerative Colitis (Disorder)
This multicenter retrospective observational study aims to develop and externally validate a machine learning model that…
Multiple LocationsEst. completion Aug 1, 2026
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A Study of CDPATH™ to Help Manage and Treat Crohn's DiseasePhase 4Recruiting
Crohn's Disease
CDPATH™ is a tool to help predict the potential for developing Crohn's disease related complications in certain adult pa…
Phoenix, United StatesEst. completion Sep 12, 2026
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Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) InpatientsRecruiting
Inflammatory Bowel Diseases
The research is studying virtual reality (VR)-directed brain-gut behavioral therapy (BGBT) as a pain treatment option fo…
Ann Arbor, United StatesEst. completion Sep 2026
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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative ColitisPhase 3Recruiting
Ulcerative Colitis
Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of…
Phoenix, United StatesEst. completion Jul 2034
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Developing a Self-Management Intervention to Improve Health Outcomes for Patients With Inflammatory Bowel DiseaseRecruiting
Inflammatory Bowel DiseasesUlcerative ColitisCrohn Disease
This research is studying whether changing an individual's behaviors may have an impact as a treatment or outcome for in…
Ann Arbor, United StatesEst. completion Mar 2028
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Predictive Efficacy of Fecal Calprotectin Assay by Magnetic Particle Chemiluminescence for Mucosal Healing in Moderate-to-Severe Ulcerative Colitis Patients Undergoing Initial Biologic Therapy(PRECAL)ENROLLING_BY_INVITATION
Ulcerative Colitis (UC)
This is a national prospective, multicenter, observational study. A total of 200 eligible patients will be enrolled from…
Beijing, ChinaCompleted Jun 30, 2027
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A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative ColitisPhase 2Recruiting
Colitis, Ulcerative
The purpose of this study is to evaluate the effectiveness and safety of ozanimod (RPC1063) in achieving and maintaining…
Phoenix, United StatesEst. completion Jul 12, 2032
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Host-microbiota Interactions in Auto-inflammatory DiseasesRecruiting
Autoinflammatory Diseases
Autoinflammatory diseases (AID) are genetic diseases responsible for excessive activation of innate immunity leading to …
Paris, FranceEst. completion Sep 2026
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A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community SettingPhase 4Recruiting
Ulcerative ColitisCrohn's Disease
Ulcerative Colitis (UC) and Crohn's Disease (CD) are long-term conditions in the gut that can cause diarrhea, swelling (…
Birmingham, United StatesEst. completion Oct 1, 2027
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Ex Vivo Study of hAMSC Secretome in Inflammatory Bowel Disease: Effects on Inflammation and Fibrosis (TARGET)Recruiting
Inflammatory Bowel Diseases
Inflammatory Bowel Diseases (IBD), including ulcerative colitis and Crohn's disease, are chronic immune-mediated disorde…
Multiple LocationsEst. completion Nov 1, 2027
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Safety and Efficacy of a STOPping Strategy Versus Classical Maintenance Dose of JAK Inhibitors in Deep Remission Patients With Ulcerative ColitisPhase 4Recruiting
Ulcerative Colitis in Remission
This phase IV, multicenter, open-label randomized controlled trial will evaluate whether a JAK inhibitor discontinuation…
Amiens, FranceEst. completion Jan 2030
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