Uveitis
Background:
\- Uveitis is a general term describing a group of inflammatory diseases of the eye. The causes of uveitis …
Bethesda, United StatesCompleted Jun 29, 2022
Inflammatory Bowel Diseases (IBD)Crohn DiseaseColitis, Ulcerative
Difficult-to-treat inflammatory bowel disease (DTT-IBD) represents a heterogeneous group of patients with treatment-refr…
Multiple LocationsEst. completion Oct 31, 2032
Inflammatory Bowel Disease
This study evaluates oral Lactobacillus reuteri as an adjunct therapy for 2 months. Endoscopic assessments will be perfo…
Suqian, ChinaCompleted Mar 30, 2026
Recurrent C. Difficile (rCDI)Ulcerative Colitis (UC)Metabolic Syndrome (MetS)
The gut microbiota plays a key role in immunity and metabolism and contributes to diseases such as recurrent C. difficil…
Rome, ItalyEst. completion Jan 19, 2029
Crohn Disease
This is an open-label, single-arm, phase 4 study to assess the safety and efficacy of mirikizumab in approximately 60 pa…
Miami, United StatesEst. completion Sep 1, 2027
Crohn's DiseaseUlcerative Colitis (UC)Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis)
Through a pilot randomized controlled trial (RCT), we aim to test the feasibility and preliminary impact of two online p…
Los Angeles, United StatesEst. completion Jul 2027
Inflammatory Bowel DiseaseUlcerative ColitisChrohn's Disease
This study will investigate in patients with Crohn s disease and ulcerative colitis how the body s immune system control…
Bethesda, United States
Colitis, Ulcerative
The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment…
Indianapolis, United StatesEst. completion Sep 8, 2030
COVID 19InfluenzaRheumatoid Arthritis (RA)Systemic Lupus ErthematosusInflammatory Bowel DiseaseSolid Organ Transplant RecipientsImmunocompromised HostPeople Living With HIV
The goal of this pragmatic embedded open-label, 2 x 2 factorial phase II randomized controlled trial is to evaluate stra…
Montreal, CanadaEst. completion Jan 31, 2028
Crohn Disease
There are currently three classes of biologic treatments approved in Canada for the management of moderate-to-severe Cro…
Calgary, CanadaEst. completion Jul 30, 2027
Poor Sleep QualityGut MicrobiomeGut HealthInflammationCircadian RhythmCircadian ClocksGut MicrobiotaWomen's HealthGut-Brain AxisBlood PressureSystemic Inflammatory Response
This study examines whether two continuous weeks of overnight active temperature regulation (via the Eight Sleep Pod) us…
Newton Center, United StatesEst. completion Dec 2026
Ulcerative Colitis (Disorder)
This multicenter longitudinal observational cohort study aims to characterize objective disease-control trajectories, tr…
Multiple LocationsEst. completion Dec 30, 2031
Inflammatory Bowel DiseaseCrohn's DiseaseUlcerative Colitis
Background:
Inflammatory bowel disease (IBD) is a term used to describe disorders that cause long-term inflammation in …
Bethesda, United StatesEst. completion Jun 1, 2036
Colitis, Ulcerative
The purpose of this observational study is to learn about the effects of etrasimod as a treatment for adult patients wit…
Mesa, United StatesEst. completion Oct 1, 2027
Ulcerative Colitis
The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with tof…
Dothan, United StatesEst. completion Jul 9, 2027
Crohn DiseasePerianal FistulaPerianal Fistula Due to Crohn's DiseasePerianal Crohn's Disease
Crohn's disease is an inflammatory bowel disease characterized by relapses and remissions, causing lesions throughout th…
Nishinomiya, JapanEst. completion Oct 13, 2028
Ulcerative Colitis
This is a multinational, multicenter, randomized, double-blind, placebo-controlled, Phase 3 induction study to evaluate …
Peoria, United StatesEst. completion May 9, 2028
Ulcerative Colitis
Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric ox…
Birmingham, United StatesEst. completion Sep 1, 2027
Antiphospholipid (aPL)-PositiveRheumatic ArthritisCeliac DiseaseFocal Segmental Glomerulosclerosis (FSGS)Membranous NephropathyCrohn Disease (CD)Type 1 Diabetes MellitusAlport SyndromePompe DiseaseAlzheimer s DiseaseUrea Cycle DisorderSystem Lupus ErythematosusHyperlipidemiaInherited ThrombophiliaSickle Cell Disease (SCD)Parkinson Disease (PD)
The primary objective of this multicenter observational registry is to characterize the clinical, epidemiological, and b…
Amman, JordanEst. completion Oct 2028
Colitis UlcerativeUlcerative Colitis
The purpose of this protocol is to evaluate the efficacy of MK-8690 in participants with moderately to severely active u…
Anaheim, United StatesEst. completion Oct 28, 2027