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Showing 564 trials for IBD
Multi-omics Dissection of Gut Microbiome Engraftment During FMTRecruiting
Recurrent C. Difficile (rCDI)Ulcerative Colitis (UC)Metabolic Syndrome (MetS)
The gut microbiota plays a key role in immunity and metabolism and contributes to diseases such as recurrent C. difficil…
Rome, ItalyEst. completion Jan 19, 2029
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Open-label Single-arm Study to Assess the Efficacy of Mirikizumab in Patients With Inflammatory Strictures Due to CDPhase 4Recruiting
Crohn Disease
This is an open-label, single-arm, phase 4 study to assess the safety and efficacy of mirikizumab in approximately 60 pa…
Miami, United StatesEst. completion Sep 1, 2027
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Immune Regulation in Ulcerative Colitis or Crohn s DiseaseRecruiting
Inflammatory Bowel DiseaseUlcerative ColitisChrohn's Disease
This study will investigate in patients with Crohn s disease and ulcerative colitis how the body s immune system control…
Bethesda, United States
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A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative ColitisPhase 2Recruiting
Colitis, Ulcerative
The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment…
Indianapolis, United StatesEst. completion Sep 8, 2030
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COVID-19 Booster and IIV Schedule in Immunocompromised HostsPhase 2Recruiting
COVID 19InfluenzaRheumatoid Arthritis (RA)Systemic Lupus ErthematosusInflammatory Bowel DiseaseSolid Organ Transplant RecipientsImmunocompromised HostPeople Living With HIV
The goal of this pragmatic embedded open-label, 2 x 2 factorial phase II randomized controlled trial is to evaluate stra…
Montreal, CanadaEst. completion Jan 31, 2028
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PATHFINDER: Evaluating the Optimal First-Line Treatment Strategy for Moderate-to-Severely Active Ileal-dominant Crohn's DiseasePhase 4Recruiting
Crohn Disease
There are currently three classes of biologic treatments approved in Canada for the management of moderate-to-severe Cro…
Calgary, CanadaEst. completion Jul 30, 2027
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The Impact of Overnight Active Temperature Regulation on the Gut Microbiome, Inflammation, and Circadian Rhythm.Recruiting
Poor Sleep QualityGut MicrobiomeGut HealthInflammationCircadian RhythmCircadian ClocksGut MicrobiotaWomen's HealthGut-Brain AxisBlood PressureSystemic Inflammatory Response
This study examines whether two continuous weeks of overnight active temperature regulation (via the Eight Sleep Pod) us…
Newton Center, United StatesEst. completion Dec 2026
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Longitudinal Immunophenotyping of Patients With Inflammatory Bowel DiseaseRecruiting
Inflammatory Bowel DiseaseCrohn's DiseaseUlcerative Colitis
Background: Inflammatory bowel disease (IBD) is a term used to describe disorders that cause long-term inflammation in …
Bethesda, United StatesEst. completion Jun 1, 2036
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An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative ColitisRecruiting
Colitis, Ulcerative
The purpose of this observational study is to learn about the effects of etrasimod as a treatment for adult patients wit…
Mesa, United StatesEst. completion Oct 1, 2027
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Risankizumab for Refractory Perianal Fistulizing Crohn's DiseasePhase 4Recruiting
Crohn DiseasePerianal FistulaPerianal Fistula Due to Crohn's DiseasePerianal Crohn's Disease
Crohn's disease is an inflammatory bowel disease characterized by relapses and remissions, causing lesions throughout th…
Nishinomiya, JapanEst. completion Oct 13, 2028
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An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative ColitisPhase 3Recruiting
Ulcerative Colitis
This is a multinational, multicenter, randomized, double-blind, placebo-controlled, Phase 3 induction study to evaluate …
Peoria, United StatesEst. completion May 9, 2028
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Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)Recruiting
Ulcerative Colitis
Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric ox…
Birmingham, United StatesEst. completion Sep 1, 2027
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A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)Phase 2Recruiting
Colitis UlcerativeUlcerative Colitis
The purpose of this protocol is to evaluate the efficacy of MK-8690 in participants with moderately to severely active u…
Anaheim, United StatesEst. completion Oct 28, 2027
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A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)Phase 3Recruiting
Crohn's Disease
The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to s…
Dothan, United StatesEst. completion Oct 30, 2028
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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's DiseasePhase 2Recruiting
Colitis, UlcerativeCrohn Disease
Study IIBD is a master protocol that will support a collection of individual sub studies that share key design component…
Scottsdale, United StatesEst. completion Jun 2027
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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative ColitisPhase 3Recruiting
Ulcerative Colitis
Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of…
Phoenix, United StatesEst. completion Jul 2034
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A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative ColitisRecruiting
Crohn DiseaseColitis, Ulcerative
The purpose of this study is to estimate and compare the incidence of overall malignancy, serious infection, and opportu…
Houston, United StatesEst. completion Aug 31, 2029
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Efficacy and Safety of Oral Controlled-Ileocolonic-Release Nicotinamide (CICR-NAM) in Patients With Mild to Moderately Active Ulcerative ColitisPhase 2Recruiting
Ulcerative Colitis, Unspecified
Double-blind, randomised, placebo-controlled phase II / III trial evaluating efficacy and safety of two different doses …
Dornstadt, GermanyEst. completion Oct 2027
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Visceral Sensitivity in IBD (Irritable Bowel Disease) and IBS (Irritable Bowel Syndrome)Recruiting
IBSUlcerative Colitis, ActiveUlcerative Colitis, Remission (3a: With IBS Symptoms, 3b: Without IBS Symptoms)Healthy ControlsCrohn's Disease, ActiveCrohn's Disease, Remission (6a: With IBS Symptoms, 6b: Without IBS Symptoms)
Aim: More insight in pathogenesis of IBS and IBD. Samples are collected in context of an European research project.
Leuven, BelgiumEst. completion Jan 2099
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Study to Assess Change in Disease Activity of Risankizumab Treatment in Adult Participants With Moderate to Severe Ulcerative ColitisRecruiting
Ulcerative Colitis
Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of…
Heidelberg, GermanyEst. completion Jul 2028
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