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Data source: ClinicalTrials.gov
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Showing 556 trials for IBD
A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier HomeostasisRecruiting
Inflammatory Bowel Disease
Crohn's Disease (CD) and Ulcerative Colitis (UC), collectively known as inflammatory bowel disease (IBD), are two of the…
Chicago, United StatesEst. completion Sep 1, 2026
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TNFi Plus Low-Dose Upadacitinib vs TNFi Intensification in Crohn's Disease With Suboptimal ResponsePhase 4Recruiting
Crohn Disease (CD)
This multicenter, randomized, controlled trial aims to evaluate the efficacy and safety of standard-dose tumor necrosis …
Guangzhou, ChinaEst. completion Dec 31, 2028
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AIM-IBD: A Microbiome-Targeted Supplement in Mild-to-Moderate Ulcerative ColitisRecruiting
Ulcerative Colitis (UC)Inflammatory Bowel Disease (IBD)Colitis
This Phase 2b randomized, double-blind, placebo-controlled, multicenter trial will evaluate the efficacy and safety of a…
Izmir, Turkey (Türkiye)Est. completion May 30, 2027
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A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative ColitisPhase 2Recruiting
Ulcerative ColitisInflammatory Bowel DiseasesColitisColitis, Ulcerative
This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active…
Canoga Park, United StatesEst. completion Jun 2026
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A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)Phase 3Recruiting
Crohn's Disease
The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to s…
Dothan, United StatesEst. completion Oct 30, 2028
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A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative ColitisPhase 3Recruiting
Colitis, Ulcerative
The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to…
Anaheim, United StatesEst. completion Aug 11, 2028
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A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Crohn Disease
The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to…
Anaheim, United StatesEst. completion Jun 12, 2028
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A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative ColitisPhase 2Recruiting
Ulcerative Colitis
The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment…
Little Rock, United StatesEst. completion Jun 16, 2029
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A Phase I Study to Evaluate the Safety/Tolerability of BDHK-2009 Tablets in Healthy AdultPhase 1Recruiting
Ulcerative Colitis (UC)Ulcerative Colitis (Disorder)Ulcerative Colitis AcuteIBD (Inflammatory Bowel Disease)CD - Crohn's Disease
A Phase 1, 2-part, randomised, double-blind, placebo-controlled, FIH study to determine the safety, tolerability, and PK…
Hangzhou, ChinaEst. completion Dec 31, 2026
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A Study to Observe Real-world Evidence of Guselkumab Treatment in Participants With Ulcerative Colitis and Crohn's Disease in the United Kingdom (UK)Recruiting
Inflammatory Bowel DiseaseColitis, UlcerativeCrohn's Disease
The purpose of this study is to evaluate the clinical effectiveness (how well the treatment works) of Guselkumab, by lin…
Harrow, United KingdomEst. completion Mar 5, 2029
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A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Crohn Disease
The purpose of this study is to assess how well guselkumab works when compared to risankizumab in participants with mode…
Dothan, United StatesEst. completion Nov 15, 2028
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A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative ColitisPhase 3Recruiting
Colitis, Ulcerative
The purpose of this protocol is to evaluate the efficacy (how well it works), safety and tolerability of oral icotrokinr…
Chandler, United StatesEst. completion Jan 14, 2028
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Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's DiseasePhase 2Recruiting
Crohn's Disease
Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tra…
Dothan, United StatesEst. completion Jan 2030
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A Study to Evaluate the Efficacy of Guselkumab in Chinese Participants With Crohn's Disease (CD)Phase 4Recruiting
Crohn Disease
The purpose of this study is to evaluate how well guselkumab works in participants with Crohn's disease (CD; a long-term…
Guangzhou, ChinaEst. completion Sep 15, 2027
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A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's DiseasePhase 2Recruiting
Crohn Disease
The purpose of this study is to evaluate how-well icotrokinra works (clinical efficacy) and how safe it is (safety) in p…
Chandler, United StatesEst. completion Sep 19, 2028
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Immune Regulation in Ulcerative Colitis or Crohn s DiseaseRecruiting
Inflammatory Bowel DiseaseUlcerative ColitisChrohn's Disease
This study will investigate in patients with Crohn s disease and ulcerative colitis how the body s immune system control…
Bethesda, United States
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A Real-World Study of Guselkumab in Chinese Participants With Ulcerative ColitisRecruiting
Colitis, Ulcerative
The purpose of this study is to assess the measurable changes in health, function, or quality of life (clinical outcomes…
Beijing, ChinaEst. completion Jun 30, 2028
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Evaluation of Therapeutic Strategy to Prevent Crohn's Disease Endoscopic poSToperatIve recurreNce Based on earlY Dosage of Faecal CalprotectinRecruiting
Crohn Disease (CD)Ileocolic ResectionPost-endoscopic Operative Reccurence
Crohn's disease (CD) (\> 200,000 patients in France) is a chronic inflammatory disease that can lead to progression of i…
Amiens, FranceEst. completion Mar 1, 2027
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A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's DiseasePhase 3Recruiting
Crohn's Disease
The purpose of this study is to evaluate the clinical and endoscopic efficacy of guselkumab in pediatric participants wi…
Los Angeles, United StatesEst. completion Oct 27, 2027
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Personalized Anti-Inflammatory Fibres in Ulcerative ColitisRecruiting
Ulcerative Colitis
The goal of this clinical trial is to determine the clinical effects of two different dietary fibre supplements, acacia …
Edmonton, CanadaEst. completion Dec 2027
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