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Data source: ClinicalTrials.gov
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Showing 1124 trials for Mental Health & Gut-Brain
Digital Single Session Intervention for Youth Mental HealthRecruiting
AnxietyDepressionConduct DisorderStress
The aim of this study is to test the effectiveness of a single-session, digital intervention teaching the principle of p…
Indianapolis, United StatesEst. completion May 31, 2027
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Serotonin Variants & Gut Microbiota in Mental Health: Pilot StudyRecruiting
Major Depressive Disorder (MDDAnxiety Disorder, GeneralizedStress Disorders, Post-TraumaticPanic Disorder
This observational pilot study investigates whether a broad panel of genetic variants relevant to the serotonin pathway …
Multiple LocationsEst. completion Jul 2027
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Feasibility and Acceptability of Peer Intervention for Improving Mental Health Among People Accessing Hormone CareRecruiting
Hormone CareMild DepressionAnxiety
The purpose of this study is to test whether the peer support program is acceptable, possible, and can improve mental he…
Ann Arbor, United StatesEst. completion Oct 2026
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Music Breathing in Enhancing Resilience Among Elders at Risk of Mental Health ProblemsRecruiting
ResilienceAnxietyDepressive SymptomLonelinessHealth-related Quality of Life
The goal of this pilot randomised controlled trial is to examine the effects of a mindfulness-based music breathing inte…
Multiple LocationsEst. completion Aug 31, 2026
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Mobile Intervention for Mental Health of Family Caregivers in ThailandRecruiting
Depressive Symptoms, Generalized Anxiety, or Psychological Stress
The primary objective of this study is to evaluate the effectiveness of the CAMMA intervention in reducing psychological…
Bangkok, ThailandEst. completion Apr 30, 2028
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Mental Health INtervention With Digital APPlications (MIND-APP): Randomized Controlled Researcher Blinded Trial Evaluating the Effectiveness of the Tankevirus and Grubl Mental Health AppsRecruiting
AnxietyDepression
The MIND-APP trial is a 3-arm randomized controlled trial (1:1:1 allocation) conducted fully remotely via a bespoke smar…
Lørenskog, NorwayEst. completion Mar 31, 2028
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Music Program for Hong Kong Adolescents: Improving Emotion Regulation and Reducing Depression, Anxiety, and LonelinessCompleted
Emotion RegulationDepressive SymptomsAnxietyLoneliness
This study is a clinical trial that aims to test and validate a music-based program called "Tuned In" in helping adolesc…
Hong Kong, Hong KongCompleted Apr 16, 2025
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The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical ActivityRecruiting
COPDDepressionAnxiety
Chronic Obstructive Pulmonary Disease (COPD) is prevalent and debilitating chronic disease in Veterans. COPD is highly c…
Boston, United StatesEst. completion Oct 31, 2026
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An Online Guided Self-help Intervention to Improve Common Mental Health Problems Among Medical ProfessionalsCompleted
Depression, Anxiety
This randomized controlled trial (RCT) aims to evaluate the effectiveness of an online guided self-help intervention dev…
Hong Kong, Hong KongCompleted Apr 1, 2026
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Cognitive Behavior Therapy in Psychiatric Inpatient CareRecruiting
Depression, Anxiety DisordersPsychiatric Inpatients
The current project aims to evaluate the extent to which psychological interventions based on Cognitive Behavioral Thera…
Stockholm, SwedenEst. completion Dec 31, 2027
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Pathway-Matched Resilience-Oriented Therapy in RwandaCompleted
Mental HealthPsychological TraumaStress Disorders, Post-TraumaticDepressionAnxietyAggressionSubstance-related DisordersPsychosocial Functioning
This pragmatic, pathway-stratified, cluster-randomized waitlist-controlled trial evaluated Resilience-Oriented Therapy (…
Ngoma, RwandaCompleted Sep 15, 2023
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A Trial of a Positive Psychology Intervention for Older Adults (RESET)Completed
Depressive SymptomsAnxietyChronic PainFatigueLonelinessStress, Psychological
The heightened vulnerability to COVID-19 of African American older adults in Detroit, Michigan and other marginalized co…
Ann Arbor, United StatesCompleted May 28, 2026
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Social Factors in the Mental Health of Young Adults: Bridging Psychological and Network AnalysisCompleted
AnxietyDepressionLonelinessStress
The central goal of this project is to produce a novel, precise, and comprehensive account of social factors in young ad…
Stanford, United StatesCompleted May 8, 2026
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Exploring Virtual Reality Adventure Training ExergamingRecruiting
Physical ActivitySedentary BehaviorDepressionCognitive FunctionPost Traumatic Stress DisorderQuality of LifeAnxiety
The current project aims to design and implement an 8-week Virtual Reality Adventure Therapy Exergaming (V-RATE) interve…
Arlington, United StatesEst. completion Aug 31, 2027
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Mobile Technologies and Post-stroke DepressionCompleted
StrokeDepression
The recent development of acute phase treatments has dramatically improved stroke functional outcome but post-stroke neu…
Bordeaux, FranceCompleted Sep 26, 2024
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Promoting Sustainable Return to Work Among Employees on Sick Leave Due to a Mental Health Condition: Evaluation of the HealthyMinds Online Group InterventionCompleted
Depression Anxiety DisorderAdjustment DisordersAdjustment Disorder With Anxious MoodAdjustment Disorder With Depressed Mood
The purpose of this clinical trial is to evaluate the impact of an online group intervention called Healthy Minds in fac…
Montreal, CanadaCompleted Mar 1, 2026
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Adapting a Health at Every Size Intervention to Obstetric CareRecruiting
Weight Stigma
Perinatal mental health disorders occur in 1 in 5 pregnancies and have significant negative intergenerational consequenc…
Worcester, United StatesEst. completion May 5, 2026
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Resilience in Adolescent DevelopmentRecruiting
Risk AssessmentResilience, PsychologicalDepressionMood DisordersAnxiety DisordersMental Health
RAD is a 10-year natural history, longitudinal, prospective assessment study of a cohort of 2,500 participants (ages 10-…
Dallas, United StatesEst. completion Dec 2031
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Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of LifeRecruiting
WellnessQuality of LifeAnxietyDepression
The study will examine the role of digital wellness modules (brief mindfulness and light to moderate physical exercise) …
New Haven, United StatesEst. completion Mar 2027
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The Nuestros Días ("Our Days") StudyRecruiting
Caregiver BurdenWell-Being, PsychologicalStress, PsychologicalDepressionAnxiety
The goal of this observational study is to understand how contextual, individual-level, and cultural factors influence t…
Birmingham, United StatesEst. completion Apr 30, 2027
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