Obesity (Disorder)
This randomized crossover clinical trial aims to evaluate the effect of a synbiotic containing Lactobacillus acidophilus…
Huixquilucan, MexicoEst. completion Feb 2, 2027
Obesity
In this study we will investigate how the medicine cagrilintide affects bone health in women after menopause with obesit…
Herlev, DenmarkEst. completion May 3, 2028
ObesityType 2 Diabetes
The trial will enroll healthy volunteers and individuals living with obesity, with and without Type 2 Diabetes. The stud…
Neuss, GermanyEst. completion Dec 2028
Endometrial NeoplasmsAtypical Endometrial HyperplasiaProgesterone Resistance
To investigate the efficacy of GnRHa plus letrozole vs Diane-35 plus metformin in non-obese progestin-insensitive early-…
Shanghai, ChinaEst. completion Mar 30, 2028
Obesity
To the best of our knowledge, this is the first study to use endoscopic band ligation for weight loss. All ligatures wil…
Giza, EgyptEst. completion Jan 1, 2029
ObesityType2diabetesGut MicrobiotaChronic Disease
The role of intestinal microbiota is becoming ever more important in the context of obesity, type II diabetes (T2D), and…
Novara, ItalyEst. completion Jan 31, 2027
Spinal Cord InjuriesObesityCardiometabolic Syndrome
The purpose of this study is to find out if receiving education regarding increased risks of cardiometabolic disease hel…
Washington D.C., United StatesEst. completion Oct 31, 2026
Obesity
This is a prospective, multi-center, standard of care registry offered to subjects in the EU only that have already agre…
Prague, CzechiaEst. completion Apr 7, 2028
ObesityOverweightType 2 Diabetes Mellitus (T2DM)
The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon-like peptide-1 (GLP-1)/gl…
Zhengzhou, ChinaEst. completion Feb 24, 2028
Childhood ObesityTreatment Adherence
The goal of this clinical trial is to evaluate the effect of adding a digi-physical treatment tool as a complement to th…
Linköping, SwedenEst. completion Apr 1, 2027
Obesity
Prospective, non-randomized study aimed at defining the initial pattern of gastric plication with the ENDOPLY System, an…
Brno, CzechiaEst. completion Oct 2027
Endometrial NeoplasmsAtypical Endometrial HyperplasiaProgesterone ResistanceObesity
To investigate the efficacy of GnRHa plus letrozole in obese progestin-insensitive EEC patients.
Shanghai, ChinaEst. completion Mar 30, 2028
Morbid ObesityMetabolic SyndromeDiabetes MellitusHypertensionObstructive Sleep Apnea of Adult
Glucagon-like peptide 1 (GLP-1) is a hormone that helps regulate blood glucose levels through improved insulin sensitivi…
Columbia, United StatesEst. completion Jul 2028
Obesity or OverweightWeight-Related ComorbidityWith/Without Diabetes Mellitus, Type 2
The study will evaluate how well AZD6234 works and how safe it is in adults with excess weight or obesity. Efficacy of A…
Escondido, United StatesEst. completion Aug 9, 2028
Weight Management
This master study protocol, Study D7260C00015, covers 2 independent, pivotal studies, Study 1 and Study 2. Each study is…
Birmingham, United StatesEst. completion Jul 31, 2028
Weight ManagementObesityExerciseWomenGut MicrobiomeMetabolomeHealthGut Microbiota
This study aims to elucidate the differences in the gut microbiome functional activity and metabolome in adult premenopa…
Washington D.C., United StatesEst. completion Jun 1, 2027
HealthyObesity
The main objective of this trial is to establish the bioequivalence of survodutide in a pre-filled syringe (reference pr…
Mannheim, GermanyEst. completion Dec 8, 2026
Obesity
Background
Obesity and physical inactivity contribute substantially to cardiovascular disease risk, diabetes, hypertens…
Bethesda, United StatesEst. completion Aug 4, 2027
ObesityOverweight
The purpose of this clinical study is to find out if NNC0113-5840 is safe for treating people with excess body weight. T…
Glendale, United StatesEst. completion Jan 31, 2027
DyslipidemiaOverweight and ObesityNutrition, Healthy
Cardiovascular disease risk factors, including higher BMIs and poor cholesterol profiles, are on the rise and contribute…
Athens, United StatesEst. completion Dec 2026