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Data source: ClinicalTrials.gov
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Showing 1477 trials for Obesity & Metabolic Health
Eating Behaviour Before, During, and After Obesity MedicationRecruiting
Obesity Type 2 Diabetes MellitusObesity & Overweight
This study will examine how eating behaviour changes during the first 18 months of treatment with obesity medications in…
Dublin, IrelandEst. completion Aug 25, 2026
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Daily Eating Patterns for Total Health StudyRecruiting
Obesity
The goal of this randomized controlled trial is to learn how the time of day when calories are eaten affects weight loss…
Knoxville, United StatesEst. completion Dec 2028
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Increased Dietary Protein Intake During GLP-1 Medication Use (in Middle-aged Women With Overweight/Obesity)Recruiting
ObesityWomen (Between 30 to 60 Years Old)
Middle-aged women with (overweight/)obesity who will begin or have begun GLP-1 medication use will be recruited to compl…
Austin, United StatesEst. completion Jun 1, 2027
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Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric DoseRecruiting
ObesityHealthy Volunteer
Background: Researchers use mixed meal tolerance tests (MMTTs) to look at how people s bodies respond to eating a meal.…
Phoenix, United StatesEst. completion Jun 30, 2027
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EBT Fruit and Vegetable PrescriptionRecruiting
Childhood ObesityObesity
Eating Better Together is a 6-month pilot program that teaches families about healthy eating and activity and provides h…
Knoxville, United StatesEst. completion Dec 2, 2026
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The Bioavailability and Effect on Pouch pH of Esomeprazole After Gastric BypassPhase 4Recruiting
ObesityGastric RefluxUlcer, Gastric
The objective of this study is to investigate the effect of Esomeprazol administered in tablets (Esomeprazol MUT Sandoz®…
Schlieren, SwitzerlandEst. completion Dec 31, 2027
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AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep ApnoeaPhase 3Recruiting
ObesityOverweightObstructive Sleep Apnoea
This study is being done to look at the efficacy and safety of NNC0487-0111 in participants with overweight or obesity, …
Gilbert, United StatesEst. completion Jun 26, 2028
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Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric SurgeryPhase 4Recruiting
Obesity
This is a randomized controlled trial employing a Sequential Multiple Assignment Randomized Trial (SMART) design to test…
Orange, United StatesEst. completion Jul 31, 2027
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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With ObesityPhase 1Recruiting
Obesity
The purpose of this study is to evaluate the safety and tolerability of single and multiple subcutaneous (SC) doses of M…
Doral, United StatesEst. completion Oct 30, 2026
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Feasibility Study for the Comprehensive Overweight/Obesity Management Pre-Kidney Transplant (COMPKT) ProgramRecruiting
Kidney Transplant; ComplicationsObesity
This project will be a single-arm feasibility study, with a treatment intervention that includes three interrelated comp…
Richmond, United StatesEst. completion Jul 2026
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Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker WomenRecruiting
Occupational StressGender Related StressSocial IsolationHypertensionPre DiabetesDiabetesObesity
The goal of this hybrid Type 1 effectiveness-implementation trial is to test the extent to which a peer support and comm…
Ellenton, United StatesEst. completion Dec 2028
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Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have DiabetesPhase 3Recruiting
ObesityOverweight
The primary objective of the study is to determine the effects of KAI-9531 subcutaneous (SC) injection once weekly compa…
Anniston, United StatesEst. completion Feb 28, 2028
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GLP-1 Therapy After Bariatric Surgery in Chinese Patients With ObesityRecruiting
Obesity
Obese patients exhibit considerable heterogeneity and complex comorbidities, making long-term effective management chall…
Beijing, ChinaEst. completion May 1, 2028
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Healthy for Two-Home Visiting (H42-HV): Health Coaching for Pregnant WomenRecruiting
Postpartum Weight RetentionPregnancy Weight GainOverweight and ObesityBehavior, Health
The purpose of this study is to compare the effectiveness of H42-HV integrated into home visiting compared with usual ho…
Baltimore, United StatesEst. completion Dec 15, 2026
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Investigating the Impact of Obesity on Pubertal Development in GirlsRecruiting
ObesityPubertyNormal Physiology
Background: Studies suggest that overweight girls may be developing breast tissue, and therefore starting puberty, earl…
Research Triangle Park, United StatesEst. completion Sep 30, 2026
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Children s Growth and Behavior StudyRecruiting
ObesityEating BehaviorsHealthy Volunteers
Background: \- Studies show that many factors affect children's eating behavior and health. These include sleep, mood, …
Bethesda, United StatesEst. completion Dec 12, 2030
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Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular SystemRecruiting
Metabolic DiseaseObesityLi-Fraumeni SyndromeCardiomyopathyAtherosclerosisInflammatory Disease
Background: \- Researchers are interested in studying individuals who have known or suspected metabolic, inflammatory o…
Washington D.C., United States
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Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and DiabetesPhase 3Recruiting
Obesity With DiabetesOverweight With Diabetes
The primary objective of this study is to demonstrate that KAI-9531 subcutaneous (SC) injection once weekly is superior …
Cullman, United StatesEst. completion Mar 27, 2028
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Physical and Behavioral Traits of Overweight and Obese AdultsRecruiting
ObesityHealthy Volunteers
This study will describe the phenotype (physical and behavioral traits) of overweight and obese people. It will characte…
Bethesda, United States
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A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants With Obesity or OverweightPhase 1Recruiting
Healthy VolunteersOverweight or Obesity
This is an investigator- and participant-blind, randomized, placebo-controlled, parallel-group, Phase I study evaluating…
Nanjing, ChinaEst. completion Dec 29, 2026
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