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Showing 277 trials for Ulcerative Colitis
A Specific Probiotic in thE MOdulation of Gut Microbiota of patieNts With Mild-to-modErate Ulcerative ColitisRecruiting
Ulcerative ColitisCrohn Disease
Probiotics are live microorganisms that provide health benefits when consumed in sufficient amounts. Traditional probiot…
Roma, ItalyEst. completion Sep 14, 2026
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Study of XmAb942 in Healthy Participants and Participants With Ulcerative ColitisPhase 1Recruiting
Ulcerative Colitis (UC)
The Phase 1 study described herein will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of XmAb…
Scottsdale, United StatesEst. completion Apr 2028
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An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body's Processing of Medicines That Rely on Cytochrome P450 Enzymes in Participants With Ulcerative ColitisPhase 1Recruiting
Active Ulcerative Colitis
The purpose of this study is to evaluate the disease-drug-drug interaction (DDDI) potential of afimkibart (also known as…
Chula Vista, United StatesEst. completion Jul 31, 2027
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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative ColitisPhase 3Recruiting
Ulcerative Colitis
Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of…
Phoenix, United StatesEst. completion Jul 2034
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Developing a Self-Management Intervention to Improve Health Outcomes for Patients With Inflammatory Bowel DiseaseRecruiting
Inflammatory Bowel DiseasesUlcerative ColitisCrohn Disease
This research is studying whether changing an individual's behaviors may have an impact as a treatment or outcome for in…
Ann Arbor, United StatesEst. completion Mar 2028
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A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative ColitisPhase 2Recruiting
Colitis, Ulcerative
The purpose of this study is to evaluate the effectiveness and safety of ozanimod (RPC1063) in achieving and maintaining…
Phoenix, United StatesEst. completion Jul 12, 2032
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A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community SettingPhase 4Recruiting
Ulcerative ColitisCrohn's Disease
Ulcerative Colitis (UC) and Crohn's Disease (CD) are long-term conditions in the gut that can cause diarrhea, swelling (…
Birmingham, United StatesEst. completion Oct 1, 2027
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Efficacy and Safety of Etrasimod in Elderly Patients With Ulcerative ColitisRecruiting
Ulcerative Colitis (Disorder)
Eligible patients will be identified in regular clinical practice. After providing thorough explanation and obtaining vo…
Komagane, JapanEst. completion Sep 30, 2027
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Treatment of UC With Novel TherapeuticsPhase 2Recruiting
Ulcerative Colitis MildUlcerative Colitis
This study is a clinical trial being done to investigate the efficacy of drug BRS201 as a treatment in patients with act…
Chestnut Hill, United StatesEst. completion Dec 1, 2026
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A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative ColitisPhase 2Recruiting
Ulcerative ColitisUlcerative Colitis Chronic
The main purpose of this study is to determine the safety and efficacy of eltrekibart and mirikizumab in adult participa…
Chandler, United StatesEst. completion Dec 2027
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Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b StudyPhase 3Recruiting
Ulcerative ColitisObesity or Overweight
The main purpose of this study is to show whether in these individuals, treatment with both mirikizumab and tirzepatide,…
Dothan, United StatesEst. completion Apr 2028
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A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)Phase 2Recruiting
Colitis UlcerativeUlcerative Colitis
The purpose of this protocol is to evaluate the efficacy of MK-8690 in participants with moderately to severely active u…
Anaheim, United StatesEst. completion Oct 28, 2027
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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's DiseasePhase 2Recruiting
Colitis, UlcerativeCrohn Disease
Study IIBD is a master protocol that will support a collection of individual sub studies that share key design component…
Scottsdale, United StatesEst. completion Jun 2027
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Evaluation of the Accuracy of Immunostaining of Claudin 2 to Detect Active or Inactive Inflammation in Endoscopic Biopsies of IBDRecruiting
Ulcerative Colitis (UC)Crohn Disease
In view of the increasing evidence of the importance of mucosal healing as a combination of endoscopic and histologic he…
San Donato Milanese, ItalyEst. completion Feb 2027
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LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:Phase 2Recruiting
Ulcerative Colitis
The main purpose of the study is to evaluate the effectiveness and safety of LY4268989 when given with mirikizumab compa…
Scottsdale, United StatesEst. completion May 2027
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LY4268989 in Adults With Moderately to Severely Active Ulcerative ColitisPhase 2Recruiting
Ulcerative Colitis (UC)Ulcerative Colitis, Active ModerateUlcerative Colitis, Active Severe
The main purpose of this study is to evaluate the safety and effectiveness of LY4268989 when compared to placebo in adul…
Phoenix, United StatesEst. completion Jun 2030
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Immune Regulation in Ulcerative Colitis or Crohn s DiseaseRecruiting
Inflammatory Bowel DiseaseUlcerative ColitisChrohn's Disease
This study will investigate in patients with Crohn s disease and ulcerative colitis how the body s immune system control…
Bethesda, United States
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Assessment and Educational Intervention to Reduce Ultra-processed Food Consumption in Pediatric Patients With IBDRecruiting
IBDCrohn Disease (CD)Ulcerative Colitis (UC)Inflammatory Bowel Disease (IBD)Ultra Processed FoodNutrition AssessmentDGBI
This study explores whether simple nutrition education can help children and teens with inflammatory bowel disease (IBD)…
Hartford, United StatesEst. completion Dec 1, 2026
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A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative ColitisPhase 2Recruiting
Ulcerative ColitisInflammatory Bowel DiseasesColitisColitis, Ulcerative
This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active…
Canoga Park, United StatesEst. completion Jun 2027
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A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative ColitisPhase 3Recruiting
Moderately to Severely Active Ulcerative Colitis
This Phase III, randomized, double-blind, multicenter, induction and maintenance study will evaluate the safety and effi…
Tampa, United StatesEst. completion Mar 31, 2030
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