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Showing 272 trials for Ulcerative Colitis
Multi-omics Dissection of Gut Microbiome Engraftment During FMTRecruiting
Recurrent C. Difficile (rCDI)Ulcerative Colitis (UC)Metabolic Syndrome (MetS)
The gut microbiota plays a key role in immunity and metabolism and contributes to diseases such as recurrent C. difficil…
Rome, ItalyEst. completion Jan 19, 2029
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Immune Regulation in Ulcerative Colitis or Crohn s DiseaseRecruiting
Inflammatory Bowel DiseaseUlcerative ColitisChrohn's Disease
This study will investigate in patients with Crohn s disease and ulcerative colitis how the body s immune system control…
Bethesda, United States
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A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative ColitisPhase 2Recruiting
Colitis, Ulcerative
The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment…
Indianapolis, United StatesEst. completion Sep 8, 2030
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Longitudinal Immunophenotyping of Patients With Inflammatory Bowel DiseaseRecruiting
Inflammatory Bowel DiseaseCrohn's DiseaseUlcerative Colitis
Background: Inflammatory bowel disease (IBD) is a term used to describe disorders that cause long-term inflammation in …
Bethesda, United StatesEst. completion Jun 1, 2036
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An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative ColitisRecruiting
Colitis, Ulcerative
The purpose of this observational study is to learn about the effects of etrasimod as a treatment for adult patients wit…
Mesa, United StatesEst. completion Oct 1, 2027
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A Study to Assess the Efficacy and Safety of Subcutaneous Induction Therapy With Afimkibart in Participants With Moderately to Severely Active Ulcerative ColitisPhase 3Recruiting
Moderately to Severely Active Ulcerative Colitis
The purpose of this study is to assess the efficacy and safety of subcutaneous induction with afimkibart in participants…
Cordova, United StatesEst. completion May 31, 2028
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An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative ColitisPhase 3Recruiting
Ulcerative Colitis
This is a multinational, multicenter, randomized, double-blind, placebo-controlled, Phase 3 induction study to evaluate …
Peoria, United StatesEst. completion May 9, 2028
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Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)Recruiting
Ulcerative Colitis
Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric ox…
Birmingham, United StatesEst. completion Sep 1, 2027
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A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)Phase 2Recruiting
Colitis UlcerativeUlcerative Colitis
The purpose of this protocol is to evaluate the efficacy of MK-8690 in participants with moderately to severely active u…
Anaheim, United StatesEst. completion Oct 28, 2027
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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's DiseasePhase 2Recruiting
Colitis, UlcerativeCrohn Disease
Study IIBD is a master protocol that will support a collection of individual sub studies that share key design component…
Scottsdale, United StatesEst. completion Jun 2027
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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative ColitisPhase 3Recruiting
Ulcerative Colitis
Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of…
Phoenix, United StatesEst. completion Jul 2034
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A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative ColitisRecruiting
Crohn DiseaseColitis, Ulcerative
The purpose of this study is to estimate and compare the incidence of overall malignancy, serious infection, and opportu…
Houston, United StatesEst. completion Aug 31, 2029
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Efficacy and Safety of Oral Controlled-Ileocolonic-Release Nicotinamide (CICR-NAM) in Patients With Mild to Moderately Active Ulcerative ColitisPhase 2Recruiting
Ulcerative Colitis, Unspecified
Double-blind, randomised, placebo-controlled phase II / III trial evaluating efficacy and safety of two different doses …
Dornstadt, GermanyEst. completion Oct 2027
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Visceral Sensitivity in IBD (Irritable Bowel Disease) and IBS (Irritable Bowel Syndrome)Recruiting
IBSUlcerative Colitis, ActiveUlcerative Colitis, Remission (3a: With IBS Symptoms, 3b: Without IBS Symptoms)Healthy ControlsCrohn's Disease, ActiveCrohn's Disease, Remission (6a: With IBS Symptoms, 6b: Without IBS Symptoms)
Aim: More insight in pathogenesis of IBS and IBD. Samples are collected in context of an European research project.
Leuven, BelgiumEst. completion Jan 2099
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Study to Assess Change in Disease Activity of Risankizumab Treatment in Adult Participants With Moderate to Severe Ulcerative ColitisRecruiting
Ulcerative Colitis
Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of…
Heidelberg, GermanyEst. completion Jul 2028
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Confirmatory Clinical Study in Active Ulcerative ColitisPhase 2Recruiting
Colitis, Ulcerative
The main goal of the study is to check if MH002 works and is safe to use. In a previous study in 45 patients with Ulcera…
Miami, United StatesEst. completion Sep 2027
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A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative ColitisPhase 2Recruiting
Ulcerative Colitis (UC)Severe Ulcerative ColitisModerate Ulcerative Colitis
The ASCENTRA-UC study is a phase 2 study testing PALI-2108 in patients with moderate to severe ulcerative colitis. Doses…
Sun City, United StatesEst. completion Oct 2027
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Efficacy and Safety of Guselkumab in Patients With Moderate-to-Severe Ulcerative ColitisRecruiting
Ulcerative Colitis (Disorder)Guselkumab
In a real-world setting, this study systematically evaluates the clinical efficacy and safety of guselkumab (GUS) in the…
Wenzhou, ChinaEst. completion Dec 31, 2028
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A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative ColitisPhase 3Recruiting
Ulcerative Colitis
The aim of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of filgotinib as a tr…
Brussels, BelgiumEst. completion Jun 2028
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A Study of MB-001 in Moderately to Severely Active Ulcerative ColitisPhase 1Recruiting
Ulcerative Colitis (UC)
The goal of this clinical trial is to learn if MB-001, an oral biologic, is able to treat patients with ulcerative colit…
Tbilisi, GeorgiaEst. completion Jul 2028
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