Melanoma Stage IV
This study looks at whether the bacteria naturally present in urine (the "urinary microbiome") can help doctors better u…
Gratwein, AustriaEst. completion May 2028
Reproductive Issues
Background:
About 1.5 million U.S. women of reproductive age are estimated to be infertile. Many more have difficulty g…
Detroit, United StatesCompleted Jun 7, 2024
Infant DevelopmentBreast FeedingEnvironmental Exposure
The goal of this observational study is to characterize and evaluate micro- and nano-plastic (MNP) exposures among mothe…
Baltimore, United StatesEst. completion Dec 31, 2026
HealthyExtracellular Vesicles
This study examines how berry consumption influences the signaling and distribution of extracellular vesicles (EVs) in t…
Oulu, FinlandEst. completion Aug 31, 2026
Functional Constipation
This study aims to evaluate the efficacy and safety of Bifidobacterium animalis subsp. lactis BLa36 in adults with funct…
Suzhou, ChinaEst. completion Nov 30, 2026
Crohn Disease (CD)
This multicenter, randomized, controlled trial aims to evaluate the efficacy and safety of standard-dose tumor necrosis …
Guangzhou, ChinaEst. completion Dec 31, 2028
Non-Communicable Disease
This umbrella protocol seeks to develop robust data registries for non-communicable diseases (NCDs) in sub-Saharan Afric…
New York, United StatesEst. completion Mar 2027
Healthy VolunteerObestity
Background:
Many people in the United States are overweight or obese. This natural history study will look into how lif…
Phoenix, United StatesEst. completion Jan 30, 2027
Ulcerative Colitis (UC)Inflammatory Bowel Disease (IBD)Colitis
This Phase 2b randomized, double-blind, placebo-controlled, multicenter trial will evaluate the efficacy and safety of a…
Izmir, Turkey (Türkiye)Est. completion May 30, 2027
Preterm BirthLow Birthweight NeonatePeriodontitisGingivitisDevelopmental Delay
The ground-breaking Prevention of Prematurity and Xylitol (PPaX) cluster randomized controlled clinical trial was conduc…
Lilongwe, MalawiEst. completion Sep 30, 2030
Anorexia of AgingMalnutrition or Risk of Malnutrition
The study aims to identify key physiological factors that differentiate older adults with healthy appetites from those e…
Singapore, SingaporeEst. completion Aug 2026
Healthy VolunteerWeight GainMetabolic EffectsIntegrase Strand Transfer Inhibitors
Background:
People with HIV take drugs to keep the amount of virus in their body low. One type of these drugs, called i…
Bethesda, United StatesEst. completion Jan 31, 2028
Constipation
To evaluate the efficacy and safety of probiotic as a food supplement in regulating bowel habits in patients with chroni…
Suzhou, ChinaEst. completion Jun 1, 2027
VitiligoHealthy
Investigators plan to perform a pilot study that aims to characterize the microbiome of human vitiligo patients with bot…
Chicago, United StatesEst. completion Dec 2026
Solid Tumor
This is a single-center, investigator-initiated, non-interventional study evaluating the role of the intestinal microbio…
Toronto, CanadaEst. completion Mar 5, 2027
Major Depressive Disorder (MDDAnxiety Disorder, GeneralizedStress Disorders, Post-TraumaticPanic Disorder
This observational pilot study investigates whether a broad panel of genetic variants relevant to the serotonin pathway …
Multiple LocationsEst. completion Jul 2027
Head and Neck Squamous Cell Carcinoma
This is a single-centre feasibility study designed to assess the safety, tolerability and engraftment of MET-4 bacterial…
Toronto, CanadaCompleted Sep 16, 2025
Staphylococcus AureusMicrobial ColonizationNeonatal Infection
This study aims to determine whether a parent-to-child nasal microbiota transplant (NMT) can seed and engraft parental o…
Baltimore, United StatesEst. completion Sep 1, 2026
Rosacea
The skin and gut microbiome of rosacea patients differs from individuals without rosacea and that the microbiome suffers…
Baltimore, United StatesEst. completion Sep 2027
Endometriosis
This study aims to test if making changes to diet can affect the pelvic pain associated with endometriosis. One group wi…
Hamilton, CanadaCompleted Jun 2026