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Data source: ClinicalTrials.gov
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Showing 11988 microbiome trials
Pre- and Post-procedure Skin Knowledge StudyRecruiting
Skin Physiology After Fractional CO₂ Laser TreatmentSkin Physiology After Thermage Treatment
The goal of this exploratory clinical trial is to characterize and compare skin clinical signs, skin physiology and subj…
Shanghai, ChinaEst. completion Jun 11, 2027
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Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS Study)Completed
Genetic DiseaseGenomics
Background: \- People with sickle cell disease and other blood disorders sometimes get chronic leg ulcers. These are wo…
Bethesda, United StatesCompleted Oct 1, 2024
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Mapping the Enhanced Landscape of Advanced Breast Cancer fOr DYnamic Treatment ApproachesPhase 2Recruiting
Breast CancerMetastatic Breast CancerLocally Advanced Breast Cancer (LABC)
MELODY is a prospective, single-arm phase II study introducing routine liquid-biopsy next-generation sequencing for pati…
Multiple LocationsEst. completion Oct 31, 2028
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A Clinical Trial to Evaluate the Effects of the NeuEve Dryness Treatment Kit on Vaginal Health, Comfort, and Quality of Life in Postmenopausal WomenRecruiting
Relieves Vaginal Dryness / Improves Self-LubricationImproves Strength & Elasticity of Vagina (Aka Collagen and Elastin)Improves Vaginal Wall ThicknessReduces Pain During SexReduces Vaginal OdorImproves Vaginal Microbiome i.e. Increases LactobacilliReduces Vaginal Itching, Improves Vaginal Burning & DischargeLowers Vaginal pH to 3.8-4.5Improves Libido / Sexual DesireImproves Orgasm / Sexual Satisfaction
This is a decentralized, single-group, open-label clinical trial evaluating a 12-week regimen of the NeuEve Dryness Trea…
Las Vegas, United StatesEst. completion Dec 2026
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The Impact of Overnight Active Temperature Regulation on the Gut Microbiome, Inflammation, and Circadian Rhythm.Recruiting
Poor Sleep QualityGut MicrobiomeGut HealthInflammationCircadian RhythmCircadian ClocksGut MicrobiotaWomen's HealthGut-Brain AxisBlood PressureSystemic Inflammatory Response
This study examines whether two continuous weeks of overnight active temperature regulation (via the Eight Sleep Pod) us…
Newton Center, United StatesEst. completion Dec 2026
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Washed Microbiota Transplantation for Type 1 Diabetes MellitusRecruiting
Type 1 Diabetes
This is a real-world study to explore the safety and the efficacy of washed microbiota transplantation (WMT) for patient…
Nanjing, ChinaEst. completion Jan 2029
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Efficacy and Safety of Auto-FMT in Preventing aGVHDCompleted
Graft Versus Host Disease, Acute
To evaluation the efficacy and safety of autologous fecal microbiota transplantation in preventing acute graft versus ho…
Suzhou, ChinaCompleted Aug 27, 2025
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Development of a Biologic Specimen Bank for the Study of Early Markers of Lung Cancer Among Tin Miners in Yunnan, ChinaCompleted
Lung Cancer
The overall goal of this project is to identify strategies to reduce lung cancer incidence and mortality. Using a high-r…
Beijing, ChinaCompleted Nov 25, 2025
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Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic AcidemiaRecruiting
Metabolic DiseasePropionic AcidemiaOrganic Acidemia
Background: People s bodies need to break down food into the chemicals. These chemicals are used for energy and growth.…
Bethesda, United StatesEst. completion Aug 31, 2036
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Study on the Effects of Probiotic on Infant Gut Microbiota and Immune RegulationRecruiting
Healthy Infants
This is a probiotic intervention study in healthy infants aged 0 - 6 months. The primary objective is to evaluate the ef…
Dalian, ChinaEst. completion Jul 11, 2027
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The Effects of Short-Chain Fatty Acids in Psychosocial Stress-Induced Impairment on Core Executive FunctionsCompleted
Executive Function
The aim of the present trial is to examine core executive functions (EFs) as a functional outcome of attenuating the cor…
Leuven, BelgiumCompleted Aug 10, 2026
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The Effects of Dietary Changes on Gut-bacteria and Fibromyalgia SymptomsCompleted
FibromyalgiaDiet, Gluten-Free
The purpose of this study is to evaluate the efficacy of two diets - gluten-free and low-FODMAP diet- in relieving sympt…
Montreal, CanadaCompleted Jun 15, 2022
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Topical Coconut Oil Application and Incidence of Sepsis in NeonatesCompleted
Late-Onset Neonatal Sepsis
The randomized control trial aims to determine the effect of twice daily application of a commonly used coconut oil to t…
Bangalore, IndiaCompleted Nov 15, 2025
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Multi-Evaluation of Dental Abutments With Different SurfacesRecruiting
EdentulismDental ImplantProsthetic Abutment
The placement of dental implants has been a routine procedure for the rehabilitation of fully or partially edentulous pa…
Kütahya, Turkey (Türkiye)Est. completion Jun 1, 2028
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Evaluation of the Effect of Regular Physical Exercise in Breast Cancer.Recruiting
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
This study, titled "Evaluation of the effect of regular physical exercise in women with breast cancer on adjuvant hormon…
San Sebastián de los Reyes, SpainEst. completion Oct 2026
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The Systemic Nature of Severe Traumatic Brain InjuryRecruiting
Severe Traumatic Brain Injury
Severe traumatic brain injury (sTBI) is a devastating condition with no targeted therapies available to prevent secondar…
Grand Rapids, United StatesEst. completion Jul 1, 2028
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Fermented Foods and Bowel Health in SCIRecruiting
Spinal Cord Injury
The goal of this clinical trial is to learn whether consuming a high fermented food diet improves bowel function and gut…
Columbus, United StatesEst. completion Jul 31, 2029
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Nutrition in Rheumatoid ArthritisENROLLING_BY_INVITATION
Rheumatoid Arthritis (RA)
Background: Individuals with Rheumatoid Arthritis (RA) often experience persistent symptoms such as pain and stiffness d…
Gothenburg, SwedenCompleted Dec 31, 2028
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Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin ResistancePhase 3Recruiting
Obesity, ChildhoodInsulin Resistance
This is a 12-month, single center, three-arm parallel design, double-blind, randomized clinical trial, to compare the ef…
Edmonton, CanadaEst. completion Feb 2027
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Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of HealthRecruiting
Post-Coronavirus Disease 19
Background: People who get COVID-19 have a wide range of symptoms. They also recover from COVID-19 in different ways. I…
Bethesda, United StatesEst. completion Dec 31, 2027
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