Malignant Glioma
This phase I/II trial tests the safety, side effects, and best dose of selinexor given in combination with standard radi…
Birmingham, United StatesEst. completion Jun 30, 2027
Preterm BirthLow Birthweight NeonatePeriodontitisGingivitisDevelopmental Delay
The ground-breaking Prevention of Prematurity and Xylitol (PPaX) cluster randomized controlled clinical trial was conduc…
Lilongwe, MalawiEst. completion Sep 30, 2030
Healthy Volunteers Only
Intestinal flora and metabolites are associated with multiple systemic diseases. Current approaches for acquiring inform…
Shanghai, ChinaCompleted Dec 31, 2025
Healthy VolunteerWeight GainMetabolic EffectsIntegrase Strand Transfer Inhibitors
Background:
People with HIV take drugs to keep the amount of virus in their body low. One type of these drugs, called i…
Bethesda, United StatesEst. completion Jan 31, 2028
Congenital Heart Disease (CHD)
The primary objective of this study is to enhance the rates of direct breast feeding (DBF) among infants with congenital…
Phoenix, United StatesEst. completion Jun 2029
Advanced Hepatocellular Carcinoma
This prospective, single-center, single-arm phase 2 study evaluates the efficacy and safety of adding oral fecal microbi…
Shenzhen, ChinaEst. completion May 20, 2027
Chronic Ulcer of Lower Extremity
Every year, 5 million people throughout Germany suffer from extensive, often chronic wounds. Cold plasma is an innovativ…
Tübingen, GermanyEst. completion Dec 31, 2026
Ulcerative Colitis (UC)Primary Sclerosing Cholangitis (PSC)Pediatric Inflammatory Bowel Diseases
The goal of this clinical trial is to learn how oral vancomycin therapy may contribute in treating paediatric inflammato…
Tampere, FinlandEst. completion Dec 31, 2032
Leukemia, Lymphocytic, AcuteLeukemia, Myeloid, AcuteLymphomaClostridium Difficile InfectionSolid Cancers
The primary objective of the study is to determine whether dietary intervention to increase fiber and decrease fat reduc…
Aurora, United StatesCompleted Jul 2, 2025
Healthy Volunteer
Background:
As people age, the cells in the pancreas that produce insulin begin to release less of this hormone, and le…
Baltimore, United StatesEst. completion Mar 31, 2027
Sensitive Skin
The purpose of this research study is to evaluate whether a marketed moisturizing cream can improve skin barrier functio…
New York, United StatesEst. completion Dec 16, 2026
Critical Illness
Patients requiring life support therapies in intensive care units are at very high risk of hospital-acquired infections.…
Calgary, CanadaEst. completion Jan 2029
PTSD - Post Traumatic Stress Disorder
The gut microbiome has been shown to impact various facets of human health, including mental health. Studies have shown …
Fort Collins, United StatesEst. completion Jul 21, 2026
Morbid ObesityMetabolic SyndromeDiabetes MellitusHypertensionObstructive Sleep Apnea of Adult
Glucagon-like peptide 1 (GLP-1) is a hormone that helps regulate blood glucose levels through improved insulin sensitivi…
Columbia, United StatesEst. completion Jul 2028
Type 1 DiabetesDiet InterventionGlucose Control
This multicenter, randomized, controlled, open-label clinical trial aims to evaluate the effects of different carbohydra…
Nanjing, ChinaEst. completion Dec 31, 2027
Healthy VolunteerObestity
Background:
Many people in the United States are overweight or obese. This natural history study will look into how lif…
Phoenix, United StatesEst. completion Jan 30, 2027
Healthy
This will be a prospective observational study aiming to investigate immune health biomarkers and fecal microbiota in 48…
Manila, PhilippinesEst. completion Jan 30, 2026
Weight ManagementObesityExerciseWomenGut MicrobiomeMetabolomeHealthGut Microbiota
This study aims to elucidate the differences in the gut microbiome functional activity and metabolome in adult premenopa…
Washington D.C., United StatesEst. completion Jun 1, 2027
Type 2 Diabetes MellitusPeriodontitisT2DMPeriodontal DiseaseType 2 DiabetesGum InflammationNon Insulin Dependent DiabetesNIDDM
Type 2 diabetes mellitus (T2DM) and periodontal (gum) disease are closely related conditions that may negatively affect …
Multiple LocationsEst. completion Sep 1, 2028
Gall StoneGall Stones, Common Bile DuctPancreatitisAcute Cholecystitis
The goal of this prospective observational study is to explore the role of the gut microbiome in patients with gallstone…
Ashford, United KingdomEst. completion Nov 13, 2025