Core Binding Factor Alpha SubunitsHematologic NeoplasmsLeukemiaLymphoma
Background:
Some blood cancers can be caused by germline variants (changes) in a person s RUNX1 gene. Germline variants…
Bethesda, United StatesEst. completion Jun 1, 2033
Recurrent C. Difficile (rCDI)Ulcerative Colitis (UC)Metabolic Syndrome (MetS)
The gut microbiota plays a key role in immunity and metabolism and contributes to diseases such as recurrent C. difficil…
Rome, ItalyEst. completion Jan 19, 2029
End-stage Renal Disease (ESRD)Kidney Transplantation
Chronic kidney disease affects approximately 10% of the world population. End-stage renal disease (ESRD) is associated w…
Lyon, FranceEst. completion Oct 15, 2028
Hematopoietic Stem Cell Transplant
Background:
Hematopoietic stem cell transplant (HSCT) is a common treatment for many cancers and other illnesses. But m…
Bethesda, United StatesEst. completion Jun 30, 2031
Type 1 Diabetes
This is a real-world study to explore the safety and the efficacy of washed microbiota transplantation (WMT) for patient…
Nanjing, ChinaEst. completion Jan 2029
Graft Versus Host Disease, Acute
To evaluation the efficacy and safety of autologous fecal microbiota transplantation in preventing acute graft versus ho…
Suzhou, ChinaCompleted Aug 27, 2025
NeoplasmsHematologic NeoplasmsHealthy Volunteers
This study will collect biological samples for use in research experiments aimed at better understanding the clinical fe…
Bethesda, United States
Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (Apeced)Alopecia Areata
Background:
Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. …
Bethesda, United StatesEst. completion Dec 1, 2027
Neutropenia, Febrile
The goal of this clinical trial is to compare a short course of antibiotics in patients in whom no bacterial infection i…
Leuven, BelgiumCompleted Mar 8, 2026
Non Small Cell Lung Cancer
This study is being done to answer the following question: Can adding a treatment called Fecal Microbiota Transplant (FM…
Multiple LocationsEst. completion Dec 31, 2030
Anorexia Nervosa
The goal of this clinical trial is to determine if Fecal Microbiota Transplantation (FMT) is effective in treating Anore…
Shanghai, ChinaEst. completion Dec 30, 2026
Lymphoma, B-CellMultiple Myeloma
Chimeric Antigen Receptor T-Cell (CAR-T) therapy has transformed the management of large B-cell lymphoma, and multiple m…
Chicago, United StatesEst. completion Sep 10, 2030
Steroid Refractory Graft Versus Host Disease
The purpose of this study is to determine the efficacy and safety of CK0802 Tregs for treatment of refractory GVHD (graf…
Multiple LocationsEst. completion Jun 30, 2028
Acute Graft Versus Host DiseaseHematopoietic and Lymphatic System Neoplasm
This randomized placebo-controlled double-blind phase II trial tests whether fecal microorganism (microbiota) transplant…
Seattle, United StatesEst. completion Aug 12, 2026
Intracerebral HemorrhageMesenchymal Stem Cell
Intracerebral hemorrhage (ICH) is a common condition with high morbidity, mortality, and disability. The current treatme…
Wuhan, ChinaEst. completion Feb 28, 2027
Clostridioides Difficile InfectionRecurrent Infection
Clostridioides difficile infection (CDI) is the leading cause of nosocomial diarrhea in Europe, with over 120,000 cases …
Annecy, FranceEst. completion Jan 7, 2028
Kidney TransplantationKidney Transplantation Recipients
People who receive a donor kidney must take drugs to prevent their bodies from attacking the new organ. These drugs are …
Naples, ItalyCompleted Oct 3, 2025
Metabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated SteatohepatitisLiver FibrosisPortal Hypertension
This prospective observational study evaluates whether endohepatology changes treatment indications in adults at high ri…
Münster, GermanyEst. completion Apr 1, 2028
Acute Graft Versus Host Disease in Intestine
This is a pilot, prospective, non-profit, multicenter, uncontrolled, open-label study to evaluate the safety and feasibi…
Bologna, ItalyEst. completion Jun 2028
Lymphoproliferative DisordersAutoimmune LymphoproliferativeImmune System DiseasesCommon Variable ImmunodeficiencyPrimary T-cell Immunodeficiency Disorders
Background:
During a transplant, blood stem cells from one person are given to someone else. The cells grow into the di…
Bethesda, United StatesEst. completion Oct 1, 2028