Core Binding Factor Alpha SubunitsHematologic NeoplasmsLeukemiaLymphoma
Background:
Some blood cancers can be caused by germline variants (changes) in a person s RUNX1 gene. Germline variants…
Bethesda, United StatesEst. completion Jun 1, 2033
Hematopoietic Stem Cell Transplant
Background:
Hematopoietic stem cell transplant (HSCT) is a common treatment for many cancers and other illnesses. But m…
Bethesda, United StatesEst. completion Jun 30, 2031
Intestinal Disease
The gut microbiota plays a crucial role in human health, influencing metabolism, immunity, and pathogen resistance. Rese…
Rome, ItalyEst. completion Mar 10, 2027
Chronic Granulomatous Disease (CGD)
Background:
X-Linked Chronic Granulomatous Disease (X-CGD) is caused by a gene mutation that makes the immune system to…
Bethesda, United StatesCompleted Sep 1, 2028
Gastro-Intestinal Disorder
Currently, ANSM recommendations govern FMT (Fecal Microbiota Transplantation) in clinical trials. The collection and val…
Paris, FranceEst. completion May 2030
Graft Versus Host DiseaseHematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
This study evaluates the factors that contribute to chronic graft-versus-host disease, which is a complication that can …
Duarte, United StatesEst. completion Jan 17, 2030
Hepatocellular CarcinomaHepatocellular CancerLiver DiseasesLiver Cancer
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide and is frequently diag…
Roma, ItalyEst. completion Sep 2028
Fecal Microbiota TransplantationCesarean SectionOverweight and Obesity
This single-center randomized controlled trial evaluates whether donor-derived fecal microbiota transplantation (FMT) ad…
Oulu, FinlandEst. completion Mar 31, 2031
Decompensated Cirrhosis
This is a phase III, multicenter, double-blind, placebo-controlled, randomized clinical trial to evaluate the safety and…
Barcelona, SpainEst. completion Jan 2029
Gastro-Intestinal Disorder
The study participant is being asked to take part in this clinical trial, a type of research study, because the particip…
Memphis, United StatesEst. completion Dec 31, 2026
Acute Graft Versus Host DiseaseHematopoietic and Lymphatic System Neoplasm
This randomized placebo-controlled double-blind phase II trial tests whether fecal microorganism (microbiota) transplant…
Seattle, United StatesEst. completion Sep 30, 2026
Rectal CancerLow Anterior Resection SyndromeFecal IncontinenceDiversion ColitisIleostomyGut Microbiota Dysbiosis
This prospective, single-center, single-arm, open-label clinical study aims to evaluate whether autologous fecal microbi…
Beijing, ChinaEst. completion May 20, 2026
ColitisDiarrheaMalignant Genitourinary System NeoplasmMelanomaLung CancerOvarian CancerUterine CancerBreast CancerCervical Cancer
This trial studies how well fecal microbiota transplantation works in treating diarrhea or colitis (inflammation of the …
Houston, United StatesEst. completion Dec 31, 2027
Helicobacter Pylori Infection
To determine whether regulating the gut microbiota can contribute to the eradication of refractory H. pylori infection.
Chengdu, ChinaEst. completion Dec 31, 2026
Alopecia AreataFecal Microbiota Transplantation (FMT)T Cell SubsetsMicrobiome
The goal of this clinical trial is to learn if fecal microbiota transplantation (FMT) works to treat alopecia areata in …
Opatija, CroatiaEst. completion Feb 2027
Clinical Stage 0 Cutaneous Melanoma AJCC v8Clinical Stage I Cutaneous Melanoma AJCC v8Clinical Stage IA Cutaneous Melanoma AJCC v8Clinical Stage IB Cutaneous Melanoma AJCC v8Clinical Stage II Cutaneous Melanoma AJCC v8Clinical Stage IIA Cutaneous Melanoma AJCC v8Clinical Stage IIB Cutaneous Melanoma AJCC v8Clinical Stage IIC Cutaneous Melanoma AJCC v8Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8ColitisLung Non-Small Cell CarcinomaMalignant Genitourinary System NeoplasmMalignant Solid NeoplasmPathologic Stage 0 Cutaneous Melanoma AJCC v8
Primary Sclerosing CholangitisLiver DiseasesCholangitis, Sclerosing
Primary sclerosing cholangitis (PSC) is a rare liver disease that damages the liver's bile ducts. Bile ducts are tiny tu…
Los Angeles, United StatesEst. completion May 31, 2029
Hematologic Neoplasms
Background:
People with blood cancers often receive blood or bone marrow transplants. But even with these treatments, t…
Bethesda, United StatesEst. completion Jul 3, 2028
Diabetes Mellitus Type 2Fecal Microbiota Transplantation (FMT)Oral Glucose Tolerance TestContinuous Glucose Monitoring
The purpose of the trial is to investigate the effect of fecal microbiota transplantation versus placebo on glycemic met…
Viborg, DenmarkEst. completion Jun 25, 2026
Liver Disease; Alcohol-RelatedCirrhosisAlcohol Use Disorder
The purpose of this research study is to test the safety, tolerability, and effectiveness of the capsules that contain b…
Richmond, United StatesEst. completion May 2027