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Data source: ClinicalTrials.gov
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Showing 260 microbiome trials
Fecal Microbiota Transplantation in Children With ASDRecruiting
Autism Spectrum Disorder
This is a single-center, randomized, double-dummy, triple-blind, placebo-controlled, three-arm parallel-group superiorit…
Shenzhen, ChinaEst. completion Dec 31, 2026
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Faecal Microbiota Transplantation After Allogeneic Stem Cell TransplantationPhase 2Recruiting
Acute Leukemia in RemissionMyelodysplastic SyndromesMyeloproliferative SyndromeHodgkin LymphomaLymphoma, Non-HodgkinMyelomaChronic Lymphocytic Leukemia
The aim of this study is to assess the Fecal Microbiota Transplantation (FMT) efficacy in the prevention of allogeneic h…
Amiens, FranceEst. completion May 2030
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Impact of Budesonide on Incidence of ≥ Gr2 Diarrhea in Multiple Myeloma (MM) Patients Undergoing Autologous Stem Cell TransplantPhase 2Recruiting
Multiple MyelomaPlasma Cell Leukemia
A randomized placebo controlled, phase 2 study of budesonide in subjects with multiple myeloma undergoing autologous ste…
Salt Lake City, United StatesEst. completion Dec 2026
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Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic MalignanciesPhase 1Recruiting
Hematologic Neoplasms
Background: People with blood cancers often receive blood or bone marrow transplants. But even with these treatments, t…
Bethesda, United StatesEst. completion Jul 3, 2028
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Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell TransplantationPhase 1Recruiting
Hematologic MalignanciesHematologic Neoplasms
Background: High-risk blood cancers (leukemias and lymphomas) often come back after treatment, and many cannot be cured…
Bethesda, United StatesEst. completion Nov 1, 2030
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Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family MembersRecruiting
NeoplasmsHematologic NeoplasmsHealthy Volunteers
This study will collect biological samples for use in research experiments aimed at better understanding the clinical fe…
Bethesda, United States
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Primary Sclerosing Cholangitis in ChildrenRecruiting
Primary Sclerosing CholangitisLiver DiseasesCholangitis, Sclerosing
Primary sclerosing cholangitis (PSC) is a rare liver disease that damages the liver's bile ducts. Bile ducts are tiny tu…
Los Angeles, United StatesEst. completion May 31, 2029
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Fecal Microbiota Transplantation in an Expanded Ulcerative Colitis PopulationPhase 1Recruiting
Ulcerative ColitisInflammatory Bowel DiseasesClostridioides Difficile Infection
This is a multi-centre, randomised controlled trial comparing fecal microbiota transplantation to placebo in an expanded…
Calgary, CanadaEst. completion Mar 1, 2028
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Effect of Preoperative Oral Carbohydrate Loading on Postoperative Outcomes in Liver Transplant PatientsRecruiting
Liver TransplantationLiver TransplantLiver Transplant SurgeryEnd Stage Liver Disease
The aim of the study is to evaluate the effect of preoperative oral carbohydrate loading on postoperative outcomes in li…
Warsaw, PolandEst. completion Aug 2028
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Fecal Microbiota Transplantation in Clostridioides Difficile Infection First Episode and First RecurrencePhase 3Recruiting
Clostridioides Difficile Infection
The clinical trial aims to evaluate the efficacy of fecal microbiota transplantation (FMT) after standard of care treatm…
Basel, SwitzerlandEst. completion Apr 1, 2027
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Fecal Microbiota Transplantation to RESCUE Patients With Unresectable Hcc Progressors to First Line Therapy With AtezolizUmaB and BevacizumabPhase 2Recruiting
Hepato Cellular Carcinoma (HCC)
The purpose of this study is to evaluate whether fecal microbiota transplantation (FMT), when administered in combinatio…
Bologna, ItalyEst. completion Jan 1, 2027
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Efficacy and Safety of Auto-FMT in Preventing aGVHDRecruiting
Graft Versus Host Disease, Acute
To evaluation the efficacy and safety of autologous fecal bacteria transplantation in preventing acute graft versus host…
Suzhou, ChinaEst. completion Mar 1, 2027
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FMT in Gut aGVHD TreatedRecruiting
Acute-graft-versus-host Disease
With the stem cell transplanting increasing, patients which effected with gut GVHD were also increased. To evaluation th…
Suzhou, ChinaEst. completion Dec 1, 2028
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Low-dose Interleukin-2 After Myocardial Infarction to Investigate Effects on Tissue-resident Regulatory T CellsRecruiting
Coronary Artery DiseaseMyocardial Infarction (MI)CABG
The primary goals of this study are to compare the differences in tissue-resident Treg gene signature for activation, pr…
Cambridge, United KingdomEst. completion Nov 1, 2028
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Fecal Microbiota Transplantation for Steroid-Refractory Acute GI GVHDPhase 2Recruiting
Graft vs Host Disease
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective treatment for various hematologic disease…
Taoyuan, TaiwanEst. completion Feb 28, 2028
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Utilization of Microbiome as Biomarkers and Therapeutics in Immuno-OncologyRecruiting
Solid Carcinoma
This is an open label, single-center, non-randomized clinical trial on utilization of microbiome as biomarkers and thera…
Seoul, South KoreaEst. completion Apr 30, 2027
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Feasibility, Safety, and Potential Efficacy of Fecal Microbiota Transplantation (FMT) for Gastrointestinal Dysfunction in Children Following Hematopoietic Cell Transplant (HCT).Phase 1Recruiting
Gastro-Intestinal Disorder
The study participant is being asked to take part in this clinical trial, a type of research study, because the particip…
Memphis, United StatesEst. completion Dec 31, 2026
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Evaluation of EXL01, a New Live Biotherapeutic Product to Prevent Recurrence of Clostridioides Difficile Infection in High-risk PatientsPhase 1Recruiting
Clostridioides Difficile InfectionRecurrent Infection
Clostridioides difficile infection (CDI) is the leading cause of nosocomial diarrhea in Europe, with over 120,000 cases …
Annecy, FranceEst. completion Jan 7, 2027
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Restoration of Antibiotics Related Infant Microbiota Perturbations by Autologous Fecal TransplantPhase 1Recruiting
Antibiotic Treatment
Antibiotics are lifesaving therapeutic drugs which have been used by adults, children, and infants alike for decades. Th…
New Brunswick, United StatesEst. completion Aug 1, 2028
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LND101 for Fecal Microbiota Transplantation in Combination With Immune Checkpoint Blockade in Advanced MelanomaPhase 2Recruiting
Melanoma
This study is being done to answer the following question: Can the chance of melanoma growing or spreading be lowered by…
Abbotsford British Columbia, CanadaEst. completion Dec 31, 2028
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