Recurrent C. Difficile (rCDI)Ulcerative Colitis (UC)Metabolic Syndrome (MetS)
The gut microbiota plays a key role in immunity and metabolism and contributes to diseases such as recurrent C. difficil…
Rome, ItalyEst. completion Jan 19, 2029
Type 1 Diabetes
This is a real-world study to explore the safety and the efficacy of washed microbiota transplantation (WMT) for patient…
Nanjing, ChinaEst. completion Jan 2029
Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (Apeced)Alopecia Areata
Background:
Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. …
Bethesda, United StatesEst. completion Dec 1, 2027
Intracerebral HemorrhageMesenchymal Stem Cell
Intracerebral hemorrhage (ICH) is a common condition with high morbidity, mortality, and disability. The current treatme…
Wuhan, ChinaEst. completion Feb 28, 2027
Clostridioides Difficile InfectionRecurrent Infection
Clostridioides difficile infection (CDI) is the leading cause of nosocomial diarrhea in Europe, with over 120,000 cases …
Annecy, FranceEst. completion Jan 7, 2028
Metabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated SteatohepatitisLiver FibrosisPortal Hypertension
This prospective observational study evaluates whether endohepatology changes treatment indications in adults at high ri…
Münster, GermanyEst. completion Apr 1, 2028
Acute Graft Versus Host Disease in Intestine
This is a pilot, prospective, non-profit, multicenter, uncontrolled, open-label study to evaluate the safety and feasibi…
Bologna, ItalyEst. completion Jun 2028
Lymphoproliferative DisordersAutoimmune LymphoproliferativeImmune System DiseasesCommon Variable ImmunodeficiencyPrimary T-cell Immunodeficiency Disorders
Background:
During a transplant, blood stem cells from one person are given to someone else. The cells grow into the di…
Bethesda, United StatesEst. completion Oct 1, 2028
Clostridium Difficile InfectionClostridioides Difficile Infection
Faecal microbiota transplantation (FMT) is used for Clostridioides difficile infection (CDI) as part of an quality impro…
Aarhus N, DenmarkEst. completion Dec 31, 2029
Peripheral Blood Stem Cell TransplantationHematopoietic Stem Cell Transplantation
Background:
Blood cancers (such as leukemias or lymphomas) often do not respond to standard treatments. A transplant of…
Duarte, United StatesEst. completion Jun 25, 2027
Malnutrition
Malnutrition is a pathological condition in which dietary intake fails to meet the body's energetic or nutritional needs…
Nanjing, ChinaEst. completion Dec 2030
Hematologic MalignanciesHematologic Neoplasms
Background:
High-risk blood cancers (leukemias and lymphomas) often come back after treatment, and many cannot be cured…
Bethesda, United StatesEst. completion Nov 1, 2030
Graft Versus Host Disease in GI Tract
Acute graft-versus-host-disease (aGvHD) is a typical complication after allogeneic hematopoetic stem cell transplantatio…
Graz, AustriaEst. completion Mar 1, 2027
Hematologic Neoplasms
Background:
Certain blood cancers can be treated with blood or bone marrow transplants. Sometimes the donor cells attac…
Bethesda, United StatesEst. completion Apr 27, 2027
Hematologic Neoplasms
Background:
People with blood cancers often receive blood or bone marrow transplants. But even with these treatments, t…
Bethesda, United StatesEst. completion Jul 3, 2028
Colonization, Asymptomatic
The goal of this clinical trial is to learn if oral capsules containing lyophilized stool from healthy donors (fecal mic…
Rijeka, CroatiaEst. completion Sep 2027
Exocrine Pancreatic Insuficiency
The goal of this clinical trial is to determine the prevalence of exocrine pancreatic insufficiency (EPI) in a populatio…
Aurora, United StatesEst. completion Aug 2027
Breast Cancer
Background: Patients with breast cancer (BC) seem to have a higher prevalence of thyroid autoimmunity (TA), and this ass…
Milan, ItalyEst. completion Dec 31, 2026
Physical AbilitiesFMT
The intestinal microbiome is a microbial system that is influenced by host genetics and environmental exposures such as …
Rehovot, IsraelEst. completion Dec 31, 2028
E Coli InfectionsAllogenic Transplant Patients
This is a Phase 1b/2a study in allogenic hematopoietic stem cell transplant patients to investigate the safety, PK, PD a…
Duarte, United StatesEst. completion Oct 2027