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Data source: ClinicalTrials.gov
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Showing 3204 microbiome trials
Research on the Use of Probiotics in the Prevention and Treatment of Inflammatory Bowel DiseaseCompleted
Inflammatory Bowel Disease
This study evaluates oral Lactobacillus reuteri as an adjunct therapy for 2 months. Endoscopic assessments will be perfo…
Suqian, ChinaCompleted Mar 30, 2026
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The Effect of Probiotics in Infantile ColicRecruiting
Infantile Colic
Academic, independent, non-commercial, multicenter study sponsored by the Department of Translational Medical Sciences (…
Naples, ItalyEst. completion Jul 2027
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Perioperative Nutrition Management in Patients Undergoing Open Posterior Lumbar SurgeryCompleted
Lumbar Degenerative DiseaseLumbar SpondylolisthesisLumbar Disc Herniation
Patients undergoing open posterior lumbar fusion surgery often experience postoperative gastrointestinal problems, such …
Kunming, ChinaCompleted Dec 31, 2025
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A Safety Trial to Evaluate an Orally Ingested Yeast Modified to Express a Tetra-specific Anti-toxin for Clostridioides DifficilePhase 1Recruiting
Clostridium Difficile Infection
This is a Phase 1, first-in-human, double-blind, placebo-controlled, adaptive-design, single-site study, involving dose …
Knoxville, United StatesEst. completion Aug 22, 2028
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Probiotics as an Adjunct to Antibiotics for Recurrent Bacterial VaginosisPhase 4Completed
Recurrent Bacterial Vaginosis
This randomized clinical trial aims to compare the recurrence of bacterial vaginosis (BV) in women receiving probiotics …
Multan, PakistanCompleted Jan 31, 2026
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Study on the Effects of Probiotic on Infant Gut Microbiota and Immune RegulationRecruiting
Healthy Infants
This is a probiotic intervention study in healthy infants aged 0 - 6 months. The primary objective is to evaluate the ef…
Dalian, ChinaEst. completion Jul 11, 2027
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Multi-strain Probiotic Effects on Self-Reported ConstipationCompleted
ConstipationProbioticProbiotic Intervention
Constipation is a prevalent gastrointestinal condition. Beyond simple lifestyle measures (e.g. increasing fibre intake, …
London, United KingdomCompleted Jul 20, 2026
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Effects of Barley and Kefir on Gut Microbiota in Physically Active AdultsRecruiting
Gut Microbiota Diversity and CompositionGut Microbiota ModulationProbioticPrebioticMetabolomics
The purpose of this randomized controlled clinical trial is to investigate whether a four-week dietary intervention cons…
Bergen, NorwayEst. completion Jun 2031
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A Study to Investigate the Effect of Probiotics (Limosilactobacillus Reuteri DSM 17938 and Limosilactobacillus Reuteri DSM 33633) on Symptoms of Viral Upper Respiratory Tract Infections in ChildrenRecruiting
Virus Diseases in Children
This study investigates the effect of Limosilactobacillus reuteri probiotic strains (DSM 17938 and DSM 33633) on symptom…
Szigetszentmiklós, HungaryEst. completion Mar 30, 2028
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Exploration of Tolerability and Dose Responses for a Yeast-based ProbioticRecruiting
Healthy Adult ParticipantsGut Health
The purpose of this study is to evaluate the tolerability and efficacy of a yeast-based dietary supplement on gastrointe…
Fort Collins, United StatesEst. completion Oct 31, 2027
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Probiotic Supplement for Recurrent UTIs in Healthy Women (L. Plantarum, L. Rhamnosus, B. Lactis)Recruiting
Recurrent Urinary Tract Infections
This randomized, double-blind, placebo-controlled trial will evaluate the efficacy of a probiotic food supplement contai…
Naples, ItalyEst. completion Apr 15, 2027
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Functional Foods for HealthRecruiting
Stress, Psychological
The gut plays an important role in supporting the immune system, and certain dietary components such as probiotics (bene…
Reading, United KingdomEst. completion Apr 1, 2027
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RE and Probiotics in MAFLD/NAFLDRecruiting
NASHNAFLDMAFLD
This project aims to evaluate the roles of the autonomic nervous system (ANS) and gut microbiota as correlates of clinic…
Multiple LocationsEst. completion Apr 10, 2031
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Investigating The Potential Of A Hay-Aged Cheese To Reduce Cholesterol As Mediated By Changes In The Gut MicrobiomeRecruiting
Cholesterol, Elevated
The goal of this intervention trial is to investigate the potential of an artisan cheese aged in hay to induce changes i…
Reading, United KingdomEst. completion Dec 2026
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Effect of the Consumption of a Probiotic Strain on the Prevention of Post-operative Recurrence in Crohn's DiseaseCompleted
Crohn's Disease
A double-blind, multicentre, stratified by centre, randomised, parallel study with two groups of adult patients operated…
Lille, FranceCompleted Mar 2007
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Effects of Probiotics on Skin Health in Healthy WomenRecruiting
Skin Aging, Dry Skin
The effect of probiotics on skin health in healthy women with dry to very dry facial skin.
Babraham, United KingdomEst. completion May 2027
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Acute Effects of a Urate-lowering Bacterial Therapeutic on Small Intestinal Transcriptomics and Glycomics in Healthy SubjectsRecruiting
HealthyHyperuricemia, Gout
This is a pilot study investigating how a novel probiotic supplement (BEO001), with and without a dietary fiber (beta-gl…
Örebro, SwedenEst. completion Sep 25, 2026
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Effect of Food-derived Active Components on Digestive Tract Health in Adults With Irritable Bowel SyndromeCompleted
Irritable Bowel Syndrome - Diarrhoea
The goal of this clinical trial is to learn if Bifidobacterium. animalis subsp. Lactis A6 Strain or resveratrol to impr…
Beijing, ChinaCompleted Mar 31, 2025
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SALI-10 Probiotic to Reduce Osteoradionecrosis and Dental Toxicity Following Radiation Therapy for Head and Neck CancerPhase 3Recruiting
Head and Neck Cancer
This Phase III randomized controlled trial will evaluate whether long-term use of the oral probiotic Streptococcus saliv…
Toronto, CanadaEst. completion Nov 1, 2031
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STUDY OF THE EFFECTS OF L. CASEI DG® (ENTEROLACTIS BABY) IN HEALTHY PRETERM AND FULL-TERM INFANTS.Completed
Gut Microbiota Modulation
The goal of this clinical trial was to learn whether giving Enterolactis Baby®, a probiotic food supplement containing L…
Roma, ItalyCompleted Apr 11, 2020
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