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Data source: ClinicalTrials.gov
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Showing 3071 microbiome trials
AIM-MET: AI-Guided Microbiome-Targeted Nutrition for Glycemic Improvement in Type 2 DiabetesRecruiting
Type 2 DiabetesDiabetes Mellitus Type 2
AIM-MET is a randomized clinical study testing whether a fixed microbiome-targeted nutritional product can improve blood…
Izmir, Turkey (Türkiye)Est. completion Mar 30, 2027
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Effects of Gallotannins on the Gut Microbiome and How it Affects Inflammatory Markers Among Obese Individuals.Recruiting
Obesity (Disorder)
The goal of this clinical trial is to understand how gallotannin-rich (GT-rich) mangoes can reduce the inflammatory mark…
Prairie View, United StatesEst. completion Jun 2026
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The Effect of Synbiotic and Diet Modification Among Overweight or Obese Hong Kong ChineseRecruiting
Obesity
Synbiotic is a nutritional supplement that contains both prebiotic and probiotic. Probiotics are beneficial microorganis…
Shatin, Hong KongEst. completion Dec 31, 2028
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Akkermansia Muciniphila (AKK) for Radiation-Induced Skin InjuryPhase 1Recruiting
Radiation-Induced Skin Injury
This study is a multicenter, open-label, Phase I single-arm clinical trial evaluating the safety and tolerability of a t…
Chengdu, ChinaEst. completion Nov 30, 2026
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Probiotic Intervention in ConstipationRecruiting
Gastrointestinal Function
To evaluate the effects of probiotic intervention on gastrointestinal function in patients with constipation after 4 wee…
Multiple LocationsEst. completion Dec 1, 2026
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Adults With ConstipationRecruiting
Constipation
This randomized, double-blind, placebo-controlled trial will assess the clinical effects of Akk09 in adults with functio…
Suzhou, ChinaEst. completion Mar 1, 2027
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Efficacy of Probiotics for OAB Patients With AnxietyRecruiting
Overactive Bladder (OAB)
The goal of this clinical trial is to learn if probiotics can help improve symptoms in adults with overactive bladder (O…
Jinan, ChinaEst. completion Dec 31, 2028
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Probiotics for Constipation Relief in AdultsRecruiting
Functional Constipation
This study aims to evaluate the efficacy and safety of Bifidobacterium animalis subsp. lactis BLa36 in adults with funct…
Suzhou, ChinaEst. completion Nov 30, 2026
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Probiotic Improve ConstipationRecruiting
Constipation
To evaluate the efficacy and safety of probiotic as a food supplement in regulating bowel habits in patients with chroni…
Suzhou, ChinaEst. completion Jun 1, 2027
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Ultramicronized Palmitoylethanolamide for Smell, Taste in Children With Autism Spectrum Disorder.Completed
AutismSmell DysfunctionTaste AlterationsSensorial Disturbance
Autism Spectrum Disorder (ASD) is frequently associated with atypical sensory processing across visual, auditory, olfact…
Latina, ItalyCompleted Oct 30, 2024
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Effect of Probiotics on Relapsing-Remitting Multiple SclerosisCompleted
Multiple Sclerosis (MS) Relapsing Remitting
This study aimed to assess the effect of probiotic supplementation on fatigue, quality of life, disability, depression a…
Cairo, EgyptCompleted Sep 1, 2024
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Oral-Spray Bacillus Spore Probiotic in Preventing and Supporting Treatment of Dental Caries in ChildrenRecruiting
Dental Caries
Despite advances in oral health care, cavities remain highly prevalent worldwide, especially among children. Conventiona…
Hà Nội, VietnamEst. completion Oct 30, 2026
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Growth, Tolerance, and Functional Biomarkers in Healthy Infants Receiving Dietary SupplementsRecruiting
Healthy Infants
This is a double-blind, randomized, placebo-controlled nutritional study aimed at investigating growth, tolerance, and f…
Multiple LocationsEst. completion Jan 31, 2027
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Rapid Recovery: Gut Microbiome Correction for PTSDRecruiting
PTSD - Post Traumatic Stress Disorder
This cohort clinical trial (RAPID RECOVERY) investigates the role of gut microbiome in mental health and the effectivene…
Uzhhorod, UkraineEst. completion Jul 1, 2025
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Functionally Enhanced Limosilactobacillus Reuteri Probiotic Preparation in Elderly Patients With Functional Bowel DisordersRecruiting
Functional Gastrointestinal Disorders
This is a single-center, open-label, single-arm interventional study designed to evaluate the effects of a functionally …
Multiple LocationsEst. completion May 2028
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Immunomodulatory Effect of Probiotics on the Immunogenicity of Anti-SARS-CoV-2 VaccinesCompleted
COVID-19Immune Response
This study aims to evaluate whether oral probiotic supplementation can modulate the immune response induced by COVID-19 …
Taipei, TaiwanCompleted Mar 31, 2022
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Evaluating the Effects of a Fermented Diet on Microbiome Diversity in Individuals With Long COVIDENROLLING_BY_INVITATION
Long COVID
The purpose of this study is to evaluate the effects of fermented foods on bacterial gut microbiome diversity of long-CO…
Rochester, United StatesCompleted Sep 30, 2025
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Modulation of Gut Microbiota Composition and Gut Permeability Profiles by Multispecies Synbiotic Supplementation in Hemodialysis PatientsRecruiting
SymbioticUremic ToxinsGut -MicrobiotaGut PermeabilityHemodialysis
Chronic kidney disease (CKD) patients undergoing maintenance hemodialysis experience profound alterations in their gut m…
Taichung, TaiwanEst. completion Dec 31, 2026
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A Study of Probiotics in IgA NephropathyCompleted
IgA Nephropathy
IgA nephropathy (IgAN) occurs when a specific form of the IgA antibody lodges on the kidneys and causes damage, which ma…
Leicester, United KingdomCompleted Aug 31, 2025
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Program Protocol for a Population That Works in Conditions of Hypobaric HypoxiaEARLY_PHASE1ENROLLING_BY_INVITATION
Changes in the Intestinal Microbiota Under Hypobaric Hypoxia ConditionsChanges in Blood Glucose Under Hypobaric Hypoxia ConditionsChanges in Body Composition Under Hypobaric Hypoxia ConditionsDetermination of Physiological Stress in Hypobaric Hypoxia
The objective of this randomized, longitudinal, single-blind, two-group parallel clinical trial is to evaluate the effec…
San Pedro de Atacama, ChileCompleted Aug 30, 2026
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