Diet TherapyHealthy Volunteers
Background:
Diet is one of the most modifiable behaviors affecting health. But diet assessment measures that are based …
Phoenix, United StatesEst. completion Jan 1, 2028
Type 2 DiabetesDiabetes Mellitus Type 2
AIM-MET is a randomized clinical study testing whether a fixed microbiome-targeted nutritional product can improve blood…
Izmir, Turkey (Türkiye)Est. completion Mar 30, 2027
Inflammatory Bowel Disease
Crohn's Disease (CD) and Ulcerative Colitis (UC), collectively known as inflammatory bowel disease (IBD), are two of the…
Chicago, United StatesEst. completion Sep 1, 2026
Cancer
Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with…
Rochester, United StatesEst. completion Mar 31, 2027
DysbiosisCardiometabolic Health Indicators
This 8-week parallel-arm randomized controlled trial (N=70; ages 6-13) will determine the impact of daily almond butter …
Tallahassee, United StatesEst. completion Aug 31, 2028
COVID-19
Type I interferon (IFN-I) production is triggered by the detection of viral molecules, such as strands of viral RNA or D…
Lyon, FranceEst. completion Jun 2027
Healthy Volunteer
Background:
As people age, the cells in the pancreas that produce insulin begin to release less of this hormone, and le…
Baltimore, United StatesEst. completion Mar 31, 2027
Autism Spectrum Disorder
This is a single-center, randomized, double-dummy, triple-blind, placebo-controlled, three-arm parallel-group superiorit…
Shenzhen, ChinaEst. completion Dec 31, 2026
Clear Cell Renal Cell CarcinomaSarcomatoid Renal Cell CarcinomaStage II Renal Cell Cancer AJCC v8Stage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8
This phase II trial compares the effect of adding a Live Biotherapeutic Product called CBM588 to pembrolizumab versus pe…
Duarte, United StatesEst. completion Oct 24, 2028
EczemaDermatitisSkin Diseases, GeneticDermatitis, AtopicSkin Diseases
Background:
\- Atopic dermatitis, or eczema, is a chronic skin disorder. Patients sometimes have infections with S. aur…
Bethesda, United StatesEst. completion Jan 1, 2027
Radiation-Induced Skin Injury
This study is a multicenter, open-label, Phase I single-arm clinical trial evaluating the safety and tolerability of a t…
Chengdu, ChinaEst. completion Nov 30, 2026
Stoma ColostomyStoma Ileostomy
Loop ileostomy and loop colostomy are both used as protective stomas after anterior resection. There is a lack of eviden…
Helsinki, FinlandEst. completion Oct 2028
Acute Leukemia in RemissionMyelodysplastic SyndromesMyeloproliferative SyndromeHodgkin LymphomaLymphoma, Non-HodgkinMyelomaChronic Lymphocytic Leukemia
The aim of this study is to assess the Fecal Microbiota Transplantation (FMT) efficacy in the prevention of allogeneic h…
Amiens, FranceEst. completion May 2030
Melanoma Stage IV
This study looks at whether the bacteria naturally present in urine (the "urinary microbiome") can help doctors better u…
Gratwein, AustriaEst. completion May 2028
Infant DevelopmentBreast FeedingEnvironmental Exposure
The goal of this observational study is to characterize and evaluate micro- and nano-plastic (MNP) exposures among mothe…
Baltimore, United StatesEst. completion Dec 31, 2026
HealthyExtracellular Vesicles
This study examines how berry consumption influences the signaling and distribution of extracellular vesicles (EVs) in t…
Oulu, FinlandEst. completion Aug 31, 2026
Crohn Disease (CD)
This multicenter, randomized, controlled trial aims to evaluate the efficacy and safety of standard-dose tumor necrosis …
Guangzhou, ChinaEst. completion Dec 31, 2028
Ulcerative Colitis (UC)Inflammatory Bowel Disease (IBD)Colitis
This Phase 2b randomized, double-blind, placebo-controlled, multicenter trial will evaluate the efficacy and safety of a…
Izmir, Turkey (Türkiye)Est. completion May 30, 2027
Preterm BirthLow Birthweight NeonatePeriodontitisGingivitisDevelopmental Delay
The ground-breaking Prevention of Prematurity and Xylitol (PPaX) cluster randomized controlled clinical trial was conduc…
Lilongwe, MalawiEst. completion Sep 30, 2030
Healthy VolunteerWeight GainMetabolic EffectsIntegrase Strand Transfer Inhibitors
Background:
People with HIV take drugs to keep the amount of virus in their body low. One type of these drugs, called i…
Bethesda, United StatesEst. completion Jan 31, 2028