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Data source: ClinicalTrials.gov
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Showing 1952 microbiome trials
The Effect of Probiotics in Infantile ColicRecruiting
Infantile Colic
Academic, independent, non-commercial, multicenter study sponsored by the Department of Translational Medical Sciences (…
Naples, ItalyEst. completion Jul 2027
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Lungs on Fire: Wildfire Smoke, Incident Diseases, Susceptible Populations, and Community Values in CanadaRecruiting
AsthmaChronic Obstructive Pulmonary Disease (COPD)Lung Cancer
Wildfire smoke (WFS) is the leading climate-related risk in Canada and the main source of harmful air pollution. While s…
Vancouver, CanadaEst. completion Aug 31, 2029
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Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical TrialRecruiting
Healthy Volunteer
Background: As people age, the cells in the pancreas that produce insulin begin to release less of this hormone, and le…
Baltimore, United StatesEst. completion Mar 31, 2027
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Multi-omics Dissection of Gut Microbiome Engraftment During FMTRecruiting
Recurrent C. Difficile (rCDI)Ulcerative Colitis (UC)Metabolic Syndrome (MetS)
The gut microbiota plays a key role in immunity and metabolism and contributes to diseases such as recurrent C. difficil…
Rome, ItalyEst. completion Jan 19, 2029
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Acquisition of Blood and Tumor Tissue Samples From Patients With Gastrointestinal CancerRecruiting
Non-GI CancersCancer of Gastrointestinal TractGastrointestinal Cancer
Background: \- Gastrointestinal cancers can occur in the throat, stomach, gallbladder, liver, pancreas, and colon. Rese…
Bethesda, United States
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Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)Recruiting
ImmunosuppressionPeriodontal DiseaseHealthy SubjectsHealthy Volunteer
Background: \- Gum disease is a condition in which the tissue around the tooth root becomes swollen and infected. This …
Bethesda, United States
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Effects of Treatments on Atopic DermatitisPhase 2Recruiting
EczemaDermatitisSkin Diseases, GeneticDermatitis, AtopicSkin Diseases
Background: \- Atopic dermatitis, or eczema, is a chronic skin disorder. Patients sometimes have infections with S. aur…
Bethesda, United StatesEst. completion Jan 1, 2027
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Pre- and Post-procedure Skin Knowledge StudyRecruiting
Skin Physiology After Fractional CO₂ Laser TreatmentSkin Physiology After Thermage Treatment
The goal of this exploratory clinical trial is to characterize and compare skin clinical signs, skin physiology and subj…
Shanghai, ChinaEst. completion Jun 11, 2027
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The Impact of Overnight Active Temperature Regulation on the Gut Microbiome, Inflammation, and Circadian Rhythm.Recruiting
Poor Sleep QualityGut MicrobiomeGut HealthInflammationCircadian RhythmCircadian ClocksGut MicrobiotaWomen's HealthGut-Brain AxisBlood PressureSystemic Inflammatory Response
This study examines whether two continuous weeks of overnight active temperature regulation (via the Eight Sleep Pod) us…
Newton Center, United StatesEst. completion Dec 2026
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Washed Microbiota Transplantation for Type 1 Diabetes MellitusRecruiting
Type 1 Diabetes
This is a real-world study to explore the safety and the efficacy of washed microbiota transplantation (WMT) for patient…
Nanjing, ChinaEst. completion Jan 2029
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Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic AcidemiaRecruiting
Metabolic DiseasePropionic AcidemiaOrganic Acidemia
Background: People s bodies need to break down food into the chemicals. These chemicals are used for energy and growth.…
Bethesda, United StatesEst. completion Aug 31, 2036
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Study on the Effects of Probiotic on Infant Gut Microbiota and Immune RegulationRecruiting
Healthy Infants
This is a probiotic intervention study in healthy infants aged 0 - 6 months. The primary objective is to evaluate the ef…
Dalian, ChinaEst. completion Jul 11, 2027
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Multi-Evaluation of Dental Abutments With Different SurfacesRecruiting
EdentulismDental ImplantProsthetic Abutment
The placement of dental implants has been a routine procedure for the rehabilitation of fully or partially edentulous pa…
Kütahya, Turkey (Türkiye)Est. completion Jun 1, 2028
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Evaluation of the Effect of Regular Physical Exercise in Breast Cancer.Recruiting
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
This study, titled "Evaluation of the effect of regular physical exercise in women with breast cancer on adjuvant hormon…
San Sebastián de los Reyes, SpainEst. completion Oct 2026
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Fermented Foods and Bowel Health in SCIRecruiting
Spinal Cord Injury
The goal of this clinical trial is to learn whether consuming a high fermented food diet improves bowel function and gut…
Columbus, United StatesEst. completion Jul 31, 2029
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Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin ResistancePhase 3Recruiting
Obesity, ChildhoodInsulin Resistance
This is a 12-month, single center, three-arm parallel design, double-blind, randomized clinical trial, to compare the ef…
Edmonton, CanadaEst. completion Feb 2027
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Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of HealthRecruiting
Post-Coronavirus Disease 19
Background: People who get COVID-19 have a wide range of symptoms. They also recover from COVID-19 in different ways. I…
Bethesda, United StatesEst. completion Dec 31, 2027
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Immersive Virtual Reality Training for Improving Cognition in Adults With Metabolic SyndromeRecruiting
Metabolic Syndrome
This study aims to evaluate the effectiveness of a multimodal intervention using immersive virtual reality (Virtual-METS…
Terrassa, SpainEst. completion Apr 1, 2027
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Milk And Growth In Children (MAGIC) Born Very Preterm: A Randomized TrialRecruiting
Prematurity
The goal of this multi-center randomized, parallel group trial is to determine the effect of human milk diets ranging be…
Birmingham, United StatesEst. completion Jan 1, 2029
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Effects of Barley and Kefir on Gut Microbiota in Physically Active AdultsRecruiting
Gut Microbiota Diversity and CompositionGut Microbiota ModulationProbioticPrebioticMetabolomics
The purpose of this randomized controlled clinical trial is to investigate whether a four-week dietary intervention cons…
Bergen, NorwayEst. completion Jun 2031
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