NCT06252649

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

RecruitingPHASE3INTERVENTIONAL

Trial Details

Start: 2024-07-17Est. Completion: 2028-09-25

Enrollment target: 450 participants

Locations

Ironwood Cancer and Research Centers Scottsdale, Chandler, Arizona, United States
Providence Saint Jude Medical Center, Fullerton, California, United States
City of Hope National Medical Center, Long Beach, California, United States
Cancer and Blood Research Center, LLC, Los Alamitos, California, United States
California Research Institute, Los Angeles, California, United States
Norwalk Hospital, Norwalk, Connecticut, United States
Cancer Specialists of North Florida - Southpoint, Jacksonville, Florida, United States
D and H Cancer Research Center, Margate, Florida, United States
Mid Florida Hematology and Oncology Centers PA, Orange City, Florida, United States
Boca Raton Clinical Research Medical Center Inc, Plantation, Florida, United States
Georgia Cancer Specialists, Atlanta, Georgia, United States
Insight Research Institute, Chicago, Illinois, United States
Hope and Healing Cancer Services, Hinsdale, Illinois, United States
Orchard Healthcare Research Inc, Skokie, Illinois, United States
Pikeville Medical Center, Pikeville, Kentucky, United States

Advanced Solid Tumors

Immune therapies work with the body's immune system to treat a number of cancers. They work with T-cells, a type of whit…

Fullerton, United StatesCompleted May 11, 2026

CancerPDAC - Pancreatic Ductal AdenocarcinomaNSCLC (Non-small Cell Lung Cancer)CRC (Colorectal Cancer)Advanced Solid Tumors

The purpose of this study is to characterize the safety and tolerability of ALTA3263 in adults with advanced solid tumor…

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