A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2) | MicrobiomeTrials
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
RecruitingPHASE3INTERVENTIONAL
Trial Details
Start: 2024-08-28Est. Completion: 2027-10-28
Enrollment target: 444 participants
Locations
Patty & George Hoag Cancer Center, Newport Beach, California, United States
UC San Diego Health - Moores Cancer Center, San Diego, California, United States
UCSF Bakar Precision Cancer Medicine Building - Thoracic Surgery and Oncology, San Francisco, California, United States
UCLA Health Santa Monica Cancer Care, Santa Monica, California, United States
The Oncology Institute of Hope and Innovation - Fort Lauderdale 17th Street, Fort Lauderdale, Florida, United States
Memorial Cancer Institute at Miramar, Miramar, Florida, United States
AdventHealth Cancer Institute Orlando, Orlando, Florida, United States
Moffitt Cancer Center - Magnolia Campus, Tampa, Florida, United States
Piedmont Healthcare - Atlanta, Atlanta, Georgia, United States
John B. Amos Cancer Center, Columbus, Georgia, United States
University of Illinois Hospital - Outpatient Cancer Care Center, Chicago, Illinois, United States
The University of Chicago Medical Center - Hyde Park - Hematology & Oncology, Chicago, Illinois, United States
UM Greenebaum Comprehensive Cancer Center, Baltimore, Maryland, United States
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Xiamen University - The First Affiliated Hospital, Xiamen, Fujian, China
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Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China
Union Hospi, Tongji Med College, Huazhong Univ. Scien&Tech, Wuhan, Hubei, China
Hubei Cancer Hospital, Wuhan, Hubei, China
Hunan Cancer Hospital - Oncology Department, Changsha, Hunan, China
NJ Drum Tower Hospital, the Affil Hos of NJ Univ Med School, Nanjing, Jiangsu, China
Jiangsu Provincial People's Hospital - The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
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Jilin Cancer Hospital, Changchun, Jilin, China
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Zhongshan Hospital, Fudan University, Shanghai, Shanghai Municipality, China
University of Electronic Science & Technology of China - Sichuan Cancer Hospital & Institute (Sichuan Provincial Tumor Hospital), Chengdu, Sichuan, China
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Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China
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Hokkaido University Hospital, Sapporo, Hokkaido, Japan
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Kobe University Hospital, Kobe, Hyōgo, Japan
Kitasato University Hospital, Sagamihara, Kanagawa, Japan
Sendai Kousei Hospital, Sendai, Miyagi, Japan
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Kindai University Hospital, Sakai, Osaka, Japan
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National Hospital Organization Kyushu Medical Center, Fukuoka, Japan
Niigata Cancer Center Hospital, Niigata, Japan
Osaka International Cancer Institute, Osaka, Japan
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Sunway Medical Centre Penang, Perai, Pulau Pinang, Malaysia
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Uniwersytecki Szpital Kliniczny w Bialymstoku, Bialystok, Poland
Swietokrzyskie Centrum Onkologii, Kielce, Poland
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Wielkopolskie Centrum Pulmonologii i Torakochirurgii, Poznan, Poland
Instytut Gruzlicy i Chorob Pluc, Warsaw, Poland
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Hospital Pedro Hispano | Clinical Research Center, Matosinhos Municipality, Porto District, Portugal
Unidade Local de Saúde de Coimbra, E.P.E. - Hospitais da Universidade de Coimbra - Serviço de Oncologia, Coimbra, Portugal
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CHULN - Hospital Pulido Valente, Lisbon, Portugal
IPO Porto, Porto, Portugal
Radiotherapy Center Cluj SRL, Florești, Comuna Floresti, Romania
Sc Oncolab Srl, Craiova, Dolj, Romania
Institutul Oncologic Prof. Dr. Alexandru Trestioreanu (IOB); Oncologie Medicală II, Bucharest, Romania
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CardioMed S.R.L., Cluj-Napoca, Romania
Institutul Oncologic Prof. Dr. Ion Chiricuta, Cluj-Napoca, Romania
Centrul de Oncologie Sfantul Nectarie, Craiova, Romania
S.C Ovidius Clinical Hospital SRL - Oncology Department, Ovidiu, Romania
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Raffles Cancer Centre, Singapore, Singapore
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Complexo Hospitalario Universitario A Coruna | Oncologia, A Coruña, Spain
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