NCT07425522

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)

RecruitingPHASE1INTERVENTIONAL

Trial Details

Start: 2026-04-21Est. Completion: 2028-11-17

Enrollment target: 93 participants

Locations

Associated Retina Consultants - Peoria - DocTrials - PPDS, Peoria, Arizona, United States
Retina-Vitreous Associates Medical Group, Beverly Hills, California, United States
Bay Area Retina Specialists Medical Group - Vestrum - PPDS, Walnut Creek, California, United States
Retina Vitreous Associates of Florida, St. Petersburg, Florida, United States
Wilmer Eye Institute, Baltimore, Maryland, United States
Erie Retina Research, LLC - 300 State St, Erie, Pennsylvania, United States
Wills Eye Hospital, Philadelphia, Pennsylvania, United States
Charles Retina Institute, Germantown, Tennessee, United States
Retina Research Institute of Texas, Abilene, Texas, United States
Austin Clinical Research, LLC, Austin, Texas, United States
Retina Consultants of Texas Westover Hills Retina Center, San Antonio, Texas, United States
Piedmont Eye Center, Lynchburg, Virginia, United States

Diabetic Retinopathy

Diabetic Retinopathy (DR) is a common eye condition caused by diabetes, where high blood sugar levels damage the blood v…

Phoenix, United StatesEst. completion Jun 2028

Diabetic Macular Edema

The dexamethasone 700 μg intravitreal implant (DEX-I) delivers dexamethasone gradually to the retina over time. It is an…

Edegem, BelgiumCompleted Aug 13, 2026

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