NCT07570173

A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)

RecruitingPHASE2, PHASE3INTERVENTIONAL

Trial Details

Start: 2026-05-18Est. Completion: 2033-10-18

Enrollment target: 340 participants

Locations

Rigshospitalet ( Site 0802), Copenhagen, Capital Region, Denmark
Aarhus Universitetshospital. Hæmatologisk afdeling ( Site 0804), Aarhus Nord, Central Jutland, Denmark
Odense Universitetshospital ( Site 0801), Odense, Region Syddanmark, Denmark
Evangelismos General Hospital of Athens ( Site 5100), Athens, Attica, Greece
General Hospital of Athens "Laiko" ( Site 5101), Athens, Attica, Greece
General Hospital of Athens "Laiko" ( Site 5104), Athens, Attica, Greece
University Hospital of Ioannina ( Site 5103), Ioannina, Greece
Rambam Health Care Campus ( Site 0903), Haifa, Israel
Haddasah Medical Center ( Site 0900), Jerusalem, Israel
Sheba Medical Center ( Site 0902), Ramat Gan, Israel
Sourasky Medical Center. ( Site 0904), Tel Aviv, Israel
Policlinico Universitario Agostino Gemelli ( Site 1003), Rome, Roma, Italy
Tokyo Metropolitan Komagome Hospital ( Site 2106), Bunkyo, Tokyo, Japan
Toranomon Hospital ( Site 2101), Minato, Tokyo, Japan
Radboud UMC ( Site 2003), Geert Grooteplein-Zuid 8, Gelderland, Netherlands

Obstructive Hypertrophic Cardiomyopathy (oHCM)

This multicenter, randomized, open-label, parallel-group, non-inferiority trial will evaluate whether sequential taperin…

Wenzhou, ChinaEst. completion Dec 2028

B-cell Acute Lymphoblastic LeukemiaDiffuse Large B-cell LymphomaBurkitt LymphomaNeuroblastomaEwing Sarcoma

Substudy 01A is part of a platform study. The purpose of this study is to assess the efficacy and safety of zilovertamab…

Los Angeles, United StatesEst. completion Mar 31, 2029

MicrobiomeTrials does not provide medical advice. Always consult your doctor before joining a clinical trial.